Evidence map›Paper›PMID 37280405›Full record

ArticleMolecular diversity2024

Microwave produced 8-methyl-1,2,4,8-tetraazaspiro[4.5]dec-2-en-3-amine derivatives: their in vitro and in silico analysis.

Parth P Patel, Navin B Patel, Manesh S Tople, Vatsal M Patel, Iqrar Ahmed, Harun Patel

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular diversity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Parth P PatelOrganic Research Laboratory, Department of Chemistry, Veer Narmad South Gujarat University, Udhana-Magdalla Road, Surat, Gujarat, 395 007, India.ORCID http://orcid.org/0000-0002-7139-070X
Navin B PatelOrganic Research Laboratory, Department of Chemistry, Veer Narmad South Gujarat University, Udhana-Magdalla Road, Surat, Gujarat, 395 007, India. drnavinbpatel@gmail.com.
Manesh S TopleOrganic Research Laboratory, Department of Chemistry, Veer Narmad South Gujarat University, Udhana-Magdalla Road, Surat, Gujarat, 395 007, India.ORCID http://orcid.org/0000-0001-7046-0764
Vatsal M PatelDepartment of Chemistry, Jamanaben Narottambhai Motiram Patel Science College, Surat, Gujarat, 395017, India.ORCID http://orcid.org/0000-0002-2286-1915
Iqrar AhmedDepartment of Pharmaceutical Chemistry, Prof. Ravindra Nikam College of Pharmacy, Gondur, Dhule, Maharashtra, 424002, India.ORCID http://orcid.org/0000-0002-7697-9572
Harun PatelDivision of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, 425405, India.ORCID http://orcid.org/0000-0003-0920-1266
Veer Narmad South Gujarat University · INACPM Dental College and Hospital · INShri Vile Parle Kelavani Mandal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compound 1 is formed by a microwave-assisted multicomponent reaction of 1-methylpiperidin-4-one, 2-amino-4-methoxy-6-methyl-1,3,5-triazine, and thiosemicarbazide, followed by the synthesis of Schiff base 2a-l with a variety of aldehydes. A comparison was made between the conventional and microwave methods, and the microwave approach was shown to be considerably superior to the classical method since it takes less time and produces higher yields. Several spectral investigations, including

Indexed as

Anti-Bacterial AgentsMicrowavesMolecular Docking SimulationAminesComputer SimulationDNA GyraseEscherichia coliMicrobial Sensitivity TestsSpiro CompoundsAminesAnti-Bacterial AgentsDNA GyraseSpiro CompoundsADME studyAntimicrobialAntitubercularMicrowave synthesisMolecular docking

Identifiers

PMID37280405
PMCPMC10243700
OpenAlexW4379522828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.