ArticleCommunications biology2023
The CLE33 peptide represses phloem differentiation via autocrine and paracrine signaling in Arabidopsis.
Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Developing a mobile RNA delivery system for grafting trait improvement.EMBO reports · 2026Article
- CLE pathways in plant development: recent advances and future perspectives.Journal of experimental botany · 2025Review
- Specificity of brassinosteroid perception and its integration at signaling crossroads in vascular development.The Plant journal : for cell and molecular biology · 2025Review
- Pan-Angiosperm Analysis of the CLE Signaling Peptide Gene Family Unveils Paths, Patterns, and Predictions of Paralog Diversification.Molecular biology and evolution · 2025Article
- Research Progress of CLE and Its Prospects in Woody Plants.Plants (Basel, Switzerland) · 2025Review
- Receptor kinase pathway signal tuning through a nontranscriptional incoherent feedforward loop.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A plant CLE peptide and its fungal mimic promote arbuscular mycorrhizal symbiosis via CRN-mediated ROS suppression.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Distinct and redundant roles of the Arabidopsis OCTOPUS gene family in plant growth beyond phloem development.Journal of experimental botany · 2025Article
- A space for time. Exploring temporal regulation of plant development across spatial scales.The Plant journal : for cell and molecular biology · 2025Review
- Peptide hormones in plants.Molecular horticulture · 2025Review
- The rise of CLAVATA: evidence for CLAVATA3 and WOX signaling in the fern gametophyte.The Plant journal : for cell and molecular biology · 2025Article
- Antagonistic CLE peptide pathways shape root meristem tissue patterning.Nature plants · 2024Article
- A major role of class III HD-ZIPs in promoting sugar beet cyst nematode parasitism in Arabidopsis.PLoS pathogens · 2024Article
- CLAVATA signaling in plant-environment interactions.Plant physiology · 2024Review
- A novel toolbox to record CLE peptide signaling.Frontiers in plant science · 2024Article
- The Interplay between Enucleated Sieve Elements and Companion Cells.Plants (Basel, Switzerland) · 2023Review
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant meristems require a constant supply of photoassimilates and hormones to the dividing meristematic cells. In the growing root, such supply is delivered by protophloem sieve elements. Due to its preeminent function for the root apical meristem, protophloem is the first tissue to differentiate. This process is regulated by a genetic circuit involving in one side the positive regulators DOF transcription factors, OCTOPUS (OPS) and BREVIX RADIX (BRX), and in the other side the negative regulators CLAVATA3/EMBRYO SURROUNDING REGION RELATED (CLE) peptides and their cognate receptors BARELY ANY MERISTEM (BAM) receptor-like kinases. brx and ops mutants harbor a discontinuous protophloem that can be fully rescued by mutation in BAM3, but is only partially rescued when all three known phloem-specific CLE genes, CLE25/26/45 are simultaneously mutated. Here we identify a CLE gene closely related to CLE45, named CLE33. We show that double mutant cle33cle45 fully suppresses brx and ops protophloem phenotype. CLE33 orthologs are found in basal angiosperms, monocots, and eudicots, and the gene duplication which gave rise to CLE45 in Arabidopsis and other Brassicaceae appears to be a recent event. We thus discovered previously unidentified Arabidopsis CLE gene that is an essential player in protophloem formation.
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