ArticleScientific reports2023
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL
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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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0cells of the map it votes in
24citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
What it found
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Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Insights into the complexity of SARS-CoV-2 MJournal of enzyme inhibition and medicinal chemistry · 2026Article
- Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems.Chemical record (New York, N.Y.) · 2026Review
- Structural Basis and Inhibitor Development of SARS-CoV-2 Papain-like Protease.Molecules (Basel, Switzerland) · 2026Review
- Selenocyanate-Containing Molecules as Trypanosoma cruzi Inhibitors: Impact of Regioisomerism, Conformational Restriction, and Second-Ring Substitution.ChemMedChem · 2026Article
- Broad-spectrum antiviral activity of ebselen.Scientific reports · 2025Article
- Redox Regulation of Microvascular Physiology and Pathophysiology: Insights into Therapeutic Strategies and Limitations.Antioxidants & redox signaling · 2025Review
- Electrolyte-Controlled Regiodivergent Continuous Flow Electroselenocyclisations.Angewandte Chemie (International ed. in English) · 2025Article
- Phototherapy of granuloma annulare: a single center retrospective study.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Recent Insights into Bioactive Dichalcogen Derivatives: From Small Molecules to Complex Materials.International journal of molecular sciences · 2025Review
- 9-aminominocycline potentiates the efficacy of EIDD-1931 and PF-332 by targeting the papain like protease enzyme of SARS-CoV-2.Scientific reports · 2025Article
- Review
- Perspective for Drug Discovery Targeting SARS Coronavirus Methyltransferases: Function, Structure and Inhibition.Journal of medicinal chemistry · 2024Review
- New insights in the mechanism of the SARS-CoV-2 MScientific reports · 2024Article
- 3-chymotrypsin-like protease in SARS-CoV-2.Bioscience reports · 2024Review
- Viral deubiquitinating proteases and the promising strategies of their inhibition.Virus research · 2024Review
- Development of a Biosafety Level 1 Cellular Assay for Identifying Small-Molecule Antivirals Targeting the Main Protease of SARS-CoV-2: Evaluation of Cellular Activity of GC376, Boceprevir, Carmofur, Ebselen, and Selenoneine.International journal of molecular sciences · 2024Article
- 4-Hydroxybenzoic Acid-Based Hydrazide-Hydrazones as Potent Growth Inhibition Agents of Laccase-Producing Phytopathogenic Fungi That Are Useful in the Protection of Oilseed Crops.Molecules (Basel, Switzerland) · 2024Article
- New cyclophilin D inhibitor rescues mitochondrial and cognitive function in Alzheimer's disease.Brain : a journal of neurology · 2024Article
- Cheminformatics approach to identify andrographolide derivatives as dual inhibitors of methyltransferases (nsp14 and nsp16) of SARS-CoV-2.Scientific reports · 2024Article
- Article
Corrections and comments
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Authors and funding
19 authors at 8 institutions in 4 countries.
Mikolaj ZmudzinskiDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland. mikolaj.zmudzinski@pwr.edu.pl.
Wioletta RutDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Kamila OlechDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Jarosław GrandaDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Mirosław GiurgDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Małgorzata Burda-GrabowskaDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Rafał KaletaDepartment of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland.
Michala ZgarbovaInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo Nám. 2, 16610, Prague, Czech Republic.
Renata KasprzykCentre of New Technologies, University of Warsaw, Banacha 2C, 02-097, Warsaw, Poland.
Linlin ZhangInstitute of Molecular Medicine, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Xinyuanyuan SunInstitute of Molecular Medicine, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Zongyang LvDepartment of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Digant NayakDepartment of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Malgorzata Kesik-BrodackaNational Medicines Institute, Ul. Chełmska 30/34, 00-725, Warsaw, Poland.
Shaun K OlsenDepartment of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
Jan WeberInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo Nám. 2, 16610, Prague, Czech Republic.
Rolf HilgenfeldInstitute of Molecular Medicine, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Jacek JemielityCentre of New Technologies, University of Warsaw, Banacha 2C, 02-097, Warsaw, Poland.
Marcin DragDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wyb. Wyspianskiego 27, 50-370, Wroclaw, Poland. marcin.drag@pwr.edu.pl.
AGH University of Krakow · PLWrocław University of Science and Technology · PLThe University of Texas Health Science Center at San Antonio · USCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZUniversity of Lübeck · DEUniversity of Warsaw · PLGerman Center for Infection Research · DENarodowy Instytut Leków · PL
Funding
Structural Biology of the Ubiquitin Conjugation SystemR01GM115568 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI OLSEN, SHAUN · 2015 to 2023
$2.7MStructure and Function of the Essential Cell Cycle Regulator Cdc34R01GM128731 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Shaun Olsen · 2019 to 2026
$2.5MNIGMS NIH HHS R01 GM115568NIGMS NIH HHS R01 GM128731
Abstract
Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against COVID-19. SARS-CoV-2 main protease (M
Indexed as
COVID-19SARS-CoV-2Antiviral AgentsCysteine EndopeptidasesHumansIsoindolesMethyltransferasesMolecular Docking SimulationOrganoselenium CompoundsPeptide HydrolasesProtease InhibitorsAntiviral AgentsCysteine EndopeptidasesebselenIsoindolesMethyltransferasesOrganoselenium CompoundsPeptide HydrolasesProtease Inhibitors
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.