ArticleScientific reports2023
Phase holograms for the three-dimensional patterning of unconstrained microparticles.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Reconfigurable acoustic tweezers based on a programmable droplet array.Microsystems & nanoengineering · 2026Article
- Strategies to control cellular spatial organization in microphysiological systems.Microsystems & nanoengineering · 2026Review
- Additive Manufacturing Techniques for Acoustic Hologram Lens Microfabrication.Micromachines · 2025Review
- xDDx: A Numerical Toolbox for Ultrasound Transducer Characterization and Design With Acoustic Holography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Improved acoustic holograms using simulated annealing.Biomicrofluidics · 2025Article
- 3D Nanofabrication via Directed Material Assembly: Mechanism, Method, and Future.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Sound innovations for biofabrication and tissue engineering.Microsystems & nanoengineering · 2024Review
- Acoustofluidic Actuation of Living Cells.Micromachines · 2024Review
- Acoustic Actuators for the Manipulation of Micro/Nanorobots: State-of-the-Art and Future Outlooks.Micromachines · 2024Review
- In vivo acoustic patterning of endothelial cells for tissue vascularization.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Acoustic radiation forces can remotely manipulate particles. Forces from a standing wave field align microscale particles along the nodal or anti-nodal locations of the field to form three-dimensional (3D) patterns. These patterns can be used to form 3D microstructures for tissue engineering applications. However, standing wave generation requires more than one transducer or a reflector, which is challenging to implement in vivo. Here, a method is developed and validated to manipulate microspheres using a travelling wave from a single transducer. Diffraction theory and an iterative angular spectrum approach are employed to design phase holograms to shape the acoustic field. The field replicates a standing wave and aligns polyethylene microspheres in water, which are analogous to cells in vivo, at pressure nodes. Using Gor'kov potential to calculate the radiation forces on the microspheres, axial forces are minimized, and transverse forces are maximized to create stable particle patterns. Pressure fields from the phase holograms and resulting particle aggregation patterns match predictions with a feature similarity index > 0.92, where 1 is a perfect match. The resulting radiation forces are comparable to those produced from a standing wave, which suggests opportunities for in vivo implementation of cell patterning toward tissue engineering applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.