Evidence map›Paper›PMID 37280118›Full record

ArticleInflammatory bowel diseases2024

Inflammatory Bowel Disease in Appalachian Kentucky: An Investigation of Outcomes and Health Care Utilization.

Christian N Rhudy, Courtney L Perry, Gregory S Hawk, Deborah R Flomenhoft, Jeffery C Talbert, Terrence A Barrett

Open access · greenAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christian N RhudyUniversity of Kentucky Healthcare, Specialty Pharmacy and Infusion Services, Lexington, Kentucky, USA.
Courtney L PerryUniversity of Kentucky College of Medicine, Department of Medicine, Division of Digestive Diseases and Nutrition, Lexington, Kentucky, USA.ORCID 0000-0001-6177-3128
Gregory S HawkUniversity of Kentucky, Dr. Bing Zhang Department of Statistics, Lexington, Kentucky, USA.
Deborah R FlomenhoftUniversity of Kentucky College of Medicine, Department of Medicine, Division of Digestive Diseases and Nutrition, Lexington, Kentucky, USA.
Jeffery C TalbertUniversity of Kentucky College of Medicine, Division of Biomedical Informatics, Lexington, Kentucky, USA.
Terrence A BarrettUniversity of Kentucky College of Medicine, Department of Medicine, Division of Digestive Diseases and Nutrition, Lexington, Kentucky, USA.
University of Kentucky · USUniversity of Kentucky HealthCare · US

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
NRSA Training CoreTL1TR001997 · NCATS · UNIVERSITY OF KENTUCKY · PI PENDERGAST, JULIE S, STOOPS, WILLIAM WALTON · 2016 to 2025
$4.2M
The Role of Crypt Fissioning in IBD Ulcer HealingR01DK095662 · NIDDK · UNIVERSITY OF KENTUCKY · PI BARRETT, TERRENCE A. · 2012 to 2024
$3.9M
Peripheral Blood Exosome Lipids as Biomarkers of Disease Activity in Crohn’s DiseaseR21DK118954 · NIDDK · UNIVERSITY OF KENTUCKY · PI BARRETT, TERRENCE A. · 2018 to 2019
$431k
The role of Axin2+ stem cells in ulcer healing during colitis.I01CX001353 · VA · VA MEDICAL CENTER - LEXINGTON, KY · PI Terrence A. Barrett · 2017 to 2026
–
CSRD VA I01 CX001353NCATS NIH HHS TL1 TR001997NCATS NIH HHS UL1 TR001998NCATS NIH HHS UL1TR001998NIDDK NIH HHS 2RO1 DK095662-10A1NIDDK NIH HHS R01 DK095662NIDDK NIH HHS R21 DK118954NIH HHS TL1TR001997
6 · The paper itself

Abstract

backgroundRural residence has been associated with a lower incidence of inflammatory bowel disease (IBD) but higher health care utilization and worse outcomes. Socioeconomic status is intrinsically tied to both IBD incidence and outcomes. Inflammatory bowel disease outcomes have not been investigated in Appalachia: a rural, economically distressed region rife with risk factors for both increased incidence and unfavorable outcomes.

methodsHospital inpatient discharge and outpatient services databases were utilized to assess outcomes in patients diagnosed with either Crohn's disease (CD) or ulcerative colitis (UC) in Kentucky. Encounters were classified by patient residence in Appalachian or non-Appalachian counties. Data were reported as crude and age-adjusted rates of visits per 100,000 population per year collected in 2016 to 2019. National inpatient discharge data from 2019, stratified by rural and urban classification codes, were utilized to compare Kentucky to national trends.

resultsCrude and age-adjusted rates of inpatient, emergency department and outpatient encounters were higher in the Appalachian cohort for all 4 years observed. Appalachian inpatient encounters are more frequently associated with a surgical procedure (Appalachian, 676, 24.7% vs non-Appalachian, 1408, 22.2%; P = .0091). In 2019, the Kentucky Appalachian cohort had significantly higher crude and age-adjusted rates of inpatient discharges for all IBD diagnoses compared with national rural and nonrural populations (crude 55.2; 95% CI, 50.9-59.5; age-adjusted 56.7; 95% CI, 52.1-61.3).

conclusionsThere is disproportionately higher IBD health care utilization in Appalachian Kentucky compared with all cohorts, including the national rural population. There is a need for aggressive investigation into root causes of these disparate outcomes and identification of barriers to appropriate IBD care.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesChild, PreschoolHumansKentuckyPatient Acceptance of Health Carehealth care disparitiesinflammatory bowel diseaseoutcomes and utilization

Identifiers

PMID37280118
PMCPMC10906357
OpenAlexW4379600734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.