Evidence map›Paper›PMID 37279992›Full record

ArticleAging2023

PZR promotes tumorigenicity of lung cancer cells by regulating cell migration and invasion via modulating oxidative stress and cell adhesion.

Ying Fu, Yuan Sui, Yuming Zhao, Jianzhuo Jiang, Xueyuan Wang, Jiarui Cui, Xueqi Fu, Shu Xing, Zhizhuang Joe Zhao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Progastrin Promotes Colorectal Cancer Stem Cell-Like Properties via the Receptor PZR.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ying FuEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Yuan SuiEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Yuming ZhaoEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Jianzhuo JiangEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Xueyuan WangEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Jiarui CuiDepartment of Laboratory Medicine, Jilin Medical University, Jilin, China.
Xueqi FuEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Shu XingEdmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun, China.
Zhizhuang Joe ZhaoDepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Jilin University · CNJilin Medical University · CNUniversity of Oklahoma Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PZR is a transmembrane glycoprotein encoded by the

Indexed as

Lung NeoplasmsAnimalsCell AdhesionCell Line, TumorCell MovementIntracellular Signaling Peptides and ProteinsMiceOxidative StressPhosphoproteinsPhosphorylationTyrosineIntracellular Signaling Peptides and ProteinsMPZL1 protein, mousePhosphoproteinsTyrosinelung cancermigrationoxidative stressPZRtumorigenicity

Identifiers

PMID37279992
PMCPMC10292906
OpenAlexW4379517648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.