Evidence map›Paper›PMID 37279966›Full record

ArticleEuropean journal of public health2023

Analgesics and ASH medications in workers increase the risk of disability pension and mortality: prospective cohort.

Lars Louis Andersen, Jonas Vinstrup, Joaquín Calatayud, Rubén López-Bueno, Thomas Clausen, Claus Manniche

Abstract read
In one paragraph

Article in European journal of public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lars Louis AndersenNational Research Centre for the Working Environment, Copenhagen, Denmark.ORCID 0000-0003-2777-8085
Jonas VinstrupNational Research Centre for the Working Environment, Copenhagen, Denmark.
Joaquín CalatayudNational Research Centre for the Working Environment, Copenhagen, Denmark.
Rubén López-BuenoNational Research Centre for the Working Environment, Copenhagen, Denmark.ORCID 0000-0002-7865-3429
Thomas ClausenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Claus MannicheDepartment of Occupational and Environmental Medicine, Institute of Clinical Research, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRelying on medication for musculoskeletal and mental disorders are common, but may have long-term consequences. This study investigates whether use of analgesics and anxiolytic/sedative/hypnotic (ASH) medication increases the risk of disability pension and mortality.

methodsAfter completing a survey in 2005, 7773 female eldercare workers were followed for 11 years in a national register. We estimated hazard ratios (HRs) for disability pension and mortality from using analgesics and ASH.

resultsDuring follow-up, 10.3% obtained disability pension and 2.4% died. For use of analgesics, a frequency-response association for the risk of disability pension existed with HR's (95% confidence interval) of 1.30 (1.07-1.57), 2.00 (1.62-2.46) and 3.47 (2.69-4.47) for monthly, weekly and daily use, respectively. For ASH, an increased risk of disability pension also existed (HR's between 1.51 and 1.64). For mortality risk, only daily use of analgesics and ASH remained significant. Population attributable fractions of analgesics and ASH, respectively, were 30% and 3% for disability pension and 5% and 3% for mortality.

conclusionsFrequent use of analgesics and ASH medication in workers increase the risk of disability pension and early death. Better management of musculoskeletal and mental health conditions, without excessive medication use, is necessary.

Indexed as

Persons with DisabilitiesAnalgesicsFemaleHumansHypnotics and SedativesPensionsProspective StudiesRisk FactorsSwedenAnalgesicsHypnotics and Sedatives

Identifiers

PMID37279966
PMCPMC10393503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.