Evidence map›Paper›PMID 37279932›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2023

Changing Mindsets About Side Effects of the COVID-19 Vaccination: A Randomized Controlled Trial.

Alia J Crum, Lauren C Heathcote, Zara Morrison, Rachael Yielder, Kari Leibowitz, Helen Petousis-Harris, Mark G Thomas, Charles G Prober, Jonathan S Berek, Keith J Petrie

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Predicting the side effects of influenza vaccination.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Alia J CrumDepartment of Psychology, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0892-1811
Lauren C HeathcoteHealth Psychology Section, Department of Psychology, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK.
Zara MorrisonDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Rachael YielderDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Kari LeibowitzDepartment of Psychology, Stanford University, Stanford, CA, USA.
Helen Petousis-HarrisDepartment of General Practice and Primary Care, University of Auckland, Auckland, New Zealand.
Mark G ThomasDepartment of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
Charles G ProberProfessor of Pediatrics, Microbiology, & Immunology, Stanford Center for Health Education, Stanford University, Stanford, CA, USA.
Jonathan S BerekStanford Women's Cancer Center, Stanford Center for Health Education, Stanford Medicine, Stanford, CA, USA.
Keith J PetrieDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
University of Auckland · NZStanford Health Care · USStanford University · USKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSide-effect concerns are a major barrier to vaccination against COVID-19 and other diseases. Identifying cost- and time-efficient interventions to improve vaccine experience and reduce vaccine hesitancy-without withholding information about side effects-is critical. PURPOSE: Determine whether a brief symptom as positive signals mindset intervention can improve vaccine experience and reduce vaccine hesitancy after the COVID-19 vaccination.

methodsEnglish-speaking adults (18+) were recruited during the 15-min wait period after receiving their second dose of the Pfizer COVID-19 vaccination and were randomly allocated to the symptom as positive signals mindset condition or the treatment as usual control. Participants in the mindset intervention viewed a 3:43-min video explaining how the body responds to vaccinations and how common side effects such as fatigue, sore arm, and fever are signs that the vaccination is helping the body boost immunity. The control group received standard vaccination center information.

resultsMindset participants (N = 260) versus controls (N = 268) reported significantly less worry about symptoms at day 3 [t(506)=2.60, p=.01, d=0.23], fewer symptoms immediately following the vaccine [t(484)=2.75, p=.006, d=0.24], and increased intentions to vaccinate against viruses like COVID-19 in the future [t(514)=-2.57, p=.01, d=0.22]. No significant differences for side-effect frequency at day 3, coping, or impact.

conclusionsThis study supports the use of a brief video aimed at reframing symptoms as positive signals to reduce worry and increase future vaccine intentions. CLINICAL TRIAL INFORMATION: Australian New Zealand Clinical Trials Registry: ACTRN12621000722897p.

Indexed as

COVID-19Drug-Related Side Effects and Adverse ReactionsAdultAustraliaCOVID-19 VaccinesHumansVaccinationCOVID-19 VaccinesCOVID-19Health CommunicationMindsetSymptomsVaccination

Identifiers

PMID37279932
PMCPMC10578416
OpenAlexW4379598674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.