Evidence map›Paper›PMID 37279763›Full record

ArticlePhysical biology2023

Approximate simulation of cortical microtubule models using dynamical graph grammars.

Eric Medwedeff, Eric Mjolsness

Abstract read
In one paragraph

Article in Physical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric MedwedeffComputational Science Research Center, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States of America.ORCID 0000-0001-7729-0614
Eric MjolsnessDepartment of Computer Science, University California Irvine, Irvine, CA 92697-3435, United States of America.ORCID 0000-0002-9085-9171

Funding

Multiscale theory of synapse function with model reduction by machine learningRF1DA055668 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MJOLSNESS, ERIC D · 2021 to 2021
$1.1M
Machine Learning for Generalized Multiscale ModelingR56AG059602 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI MJOLSNESS, ERIC D · 2018 to 2018
$619k
NIA NIH HHS R56 AG059602NIDA NIH HHS RF1 DA055668
6 · The paper itself

Abstract

Dynamical graph grammars (DGGs) are capable of modeling and simulating the dynamics of the cortical microtubule array (CMA) in plant cells by using an exact simulation algorithm derived from a master equation; however, the exact method is slow for large systems. We present preliminary work on an approximate simulation algorithm that is compatible with the DGG formalism. The approximate simulation algorithm uses a spatial decomposition of the domain at the level of the system's time-evolution operator, to gain efficiency at the cost of some reactions firing out of order, which may introduce errors. The decomposition is more coarsely partitioned by effective dimension (

Indexed as

AlgorithmsComputer Simulationcell complexcortical microtubule arraydynamic graph grammarslocal graph dynamicsnumerical computingoperator splittingsimulation algorithm

Identifiers

PMID37279763
PMCPMC11216692

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.