Evidence map›Paper›PMID 37279296›Full record

Observational studyThyroid : official journal of the American Thyroid Association2023

Determinants for Thyroid Hormone Replacement Therapy in Subclinical Hypothyroidism: A Multicenter Electronic Health Records-Based Study.

Freddy J K Toloza, Omar M El Kawkgi, Horace J Spencer, Sherin Elsa Mathews, Andrea Garcia, Augusto Gamboa, Nabeel Mirza, Sneha Mohan, Sebastian Vallejo, Marija Bogojevic and 4 more

Registry-linked trialOpen access · greenAbstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Thyroid : official journal of the American Thyroid Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04288115 (Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04288115 phase4completednot on this map

Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism: a Pilot Randomized, Double-blinded, Placebo-controlled Study

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2021 to 2022Enrolled52ConditionsSubclinical HypothyroidismArmsLevothyroxine, Placebo
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Freddy J K TolozaDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Omar M El KawkgiKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-2923-6829
Horace J SpencerDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Sherin Elsa MathewsDivision of Endocrinology, Department of Medicine, University of Florida, Gainesville, Florida, USA.
Andrea GarciaKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Augusto GamboaPlataforma INVEST Medicina UANL-KER Unit (KER Unit México), School of Medicine, Universidad Autónoma de Nuevo León, Monterrey, Mexico.ORCID 0000-0003-2298-7443
Nabeel MirzaDivision of Endocrinology, Department of Medicine, University of Florida, Gainesville, Florida, USA.
Sneha MohanDepartment of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Sebastian VallejoKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Marija BogojevicKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Rene Rodriguez-GutierrezKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Naykky M Singh OspinaKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Juan P BritoKnowledge and Evaluation Research Unit, Division of Endocrinology, Diabetes, Metabolism and Nutrition, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Spyridoula MarakaDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Mayo Clinic · USMayo Clinic in Florida · USUniversity of Florida · USUniversidad Autónoma de Nuevo León · MXCentral Arkansas Veterans Healthcare System · USMetroWest Medical Center · USUniversity of Arkansas for Medical Sciences · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Adequate selection of patients for thyroid biopsy: evaluation of a shared decision making conversation aidK08CA248972 · NCI · UNIVERSITY OF FLORIDA · PI SINGH OSPINA, NAYKKY · 2020 to 2024
$1.1M
Discontinuation of levothyroxine therapy for patients with subclinical hypothyroidism: a pilot randomized, double-blinded, placebo-controlled studyI21HX003268 · VA · CENTRAL ARKANSAS VETERANS HLTHCARE SYS · PI MARAKA, SPYRIDOULA · 2021 to 2022
–
HSRD VA I21 HX003268NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR003107NCI NIH HHS K08 CA248972
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Electronic Health RecordsHypothyroidismAdultFemaleHormone Replacement TherapyHumansMaleThyrotropinThyroxineThyrotropinThyroxineautoimmunitylevothyroxinesubclinical hypothyroidismthyroid

Identifiers

PMID37279296
PMCPMC10516235
OpenAlexW4379517157

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.