Evidence map›Paper›PMID 37279147›Full record

ArticleJournal of medicinal chemistry2023

Serum-Stable Gold(III) Bisphosphine Complex Induces Mild Mitochondrial Uncoupling and In Vivo Antitumor Potency in Triple Negative Breast Cancer.

Adedamola S Arojojoye, Chibuzor Olelewe, Sailajah Gukathasan, Jong H Kim, Hemendra Vekaria, Sean Parkin, Patrick G Sullivan, Samuel G Awuah

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. ACS nanoscience Au · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Adedamola S ArojojoyeDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0003-3076-264X
Chibuzor OleleweDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Sailajah GukathasanDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Jong H KimDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Hemendra VekariaSpinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky 40536, United States.
Sean ParkinDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.
Patrick G SullivanSpinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky 40536, United States.ORCID 0000-0001-7418-4760
Samuel G AwuahDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506, United States.ORCID 0000-0003-4947-7283
University of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Understanding the role of anti-apolipoprotein A-I antibodies in atherosclerotic cardiovascular diseaseP20GM130456 · NIGMS · UNIVERSITY OF KENTUCKY · PI Jon Scott Thorson · 2020 to 2026
$18.7M
Gold-derived Therapeutic Compounds for Disease ApplicationR01CA258421 · NCI · UNIVERSITY OF KENTUCKY · PI AWUAH, SAMUEL GORMAN · 2021 to 2025
$1.7M
NCI NIH HHS P30 CA177558NCI NIH HHS R01 CA258421NIGMS NIH HHS P20 GM130456
6 · The paper itself

Abstract

The preparation of cyclometalated complexes offers a path to stable materials, catalysts, and therapeutic agents. Here, we explore the anticancer potential of novel biphenyl organogold(III) cationic complexes supported by diverse bisphosphine ligands,

Indexed as

Antineoplastic AgentsTriple Negative Breast NeoplasmsAnimalsApoptosisBiphenyl CompoundsCell Line, TumorCell ProliferationGoldHumansMiceMitochondriaOrganogold CompoundsSerumAntineoplastic AgentsbiphenylBiphenyl CompoundsGoldOrganogold Compounds

Identifiers

PMID37279147
PMCPMC10317555
OpenAlexW4379598459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.