ArticleNatural products and bioprospecting2023
Structural characterizations and α-glucosidase inhibitory activities of four Lepidium meyenii polysaccharides with different molecular weights.
Article in Natural products and bioprospecting, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 12 citations in OpenAlex.
- Maca polysaccharides: structural diversity, biological activities, and structure-activity relationships.Natural products and bioprospecting · 2026Review
- Partial characterization and evaluation of antioxidant and antibacterial activities of a water soluble polysaccharide isolated from Euphorbia hebecarpa roots.Scientific reports · 2026Article
- Separation, Purification, Structural Characterization and Hypoglycemic Effect Study of HomogeneousFoods (Basel, Switzerland) · 2026Article
- Global Research Status of Maca (Drug design, development and therapy · 2025Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Four polysaccharides (MCPa, MCPb, MCPc, MCPd) were obtained from Lepidium meyenii Walp. Their structures were characterized by chemical and instrumental methods including total sugar, uronic acid and protein content determination, UV, IR and NMR spectroscopy, as well as monosaccharide composition determination and methylation analyses. Four polysaccharides were a group of glucans with different molecular weights ranging from 3.12 to 14.4 kDa, and shared a similar backbone chain consisting of (1→4)-glucose linkages with branches attached to C-3 and C-6. Furthermore, bioactivity assay showed that MCPs had concentration-dependent inhibitory activity on α-glucosidase. MCPb (Mw = 10.1 kDa) and MCPc (Mw = 5.62 kDa) with moderate molecular weights exhibited higher inhibitory activity compared with MCPa and MCPd.
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