ArticleCalcified tissue international2023
Validation of Fourier Transform Infrared Microspectroscopy for the Evaluation of Enzymatic Cross-Linking of Bone Collagen.
Article in Calcified tissue international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Impaired organic and mineral extracellular matrix composition in early-onset osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Polyphenol-functionalized silver nanoparticles promote differential remineralization and reinforcement of demineralized dentin.Journal of applied oral science : revista FOB · 2026Article
- Fourier Transform Infrared Imaging of Bone.Methods in molecular biology (Clifton, N.J.) · 2025Article
- From Structure to Strength: Analyzing the Impact of Sulfuric Acid on Pig Bone Demineralization Through FTIR, LIBS, and AAS.International journal of molecular sciences · 2024Article
- Machine learning-assisted mid-infrared spectrochemical fibrillar collagen imaging in clinical tissues.Journal of biomedical optics · 2024Article
- Machine learning assisted mid-infrared spectrochemical fibrillar collagen imaging in clinical tissues.bioRxiv : the preprint server for biology · 2024Article
- Article
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2 authors at 1 institution in 1 country.
Funding
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Abstract
Enzymatic cross-linking of the bone collagen is important to resist to crack growth and to increased flexural strength. In the present study, we proposed a new method for assessment of enzymatic cross-link based on Fourier transform infrared (FTIR) microspectroscopy that takes into account secondary structure of type I collagen. Briefly, femurs were collected from sham or ovariectomized mice and subjected either to high-performance liquid chromatography-mass spectrometry or embedded in polymethylmethacrylate, cut and analyzed by FTIR microspectroscopy. FTIR acquisition was recorded before and after ultraviolet (UV) exposure or acid treatment. In addition, femurs from a second animal study were used to compare gene expression of Plod2 and Lox enzymes and enzymatic cross-links determined by FTIR microspectroscopy. We evidenced here that intensities and areas of subbands located at ~1660, ~1680, and ~1690 cm
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