Evidence map›Paper›PMID 37277946›Full record

ArticleMolecular ecology2023

Barriers to chimpanzee gene flow at the south-east edge of their distribution.

Noémie Bonnin, Alex K Piel, Richard P Brown, Yingying Li, Andrew Jesse Connell, Alexa N Avitto, Jean P Boubli, Adrienne Chitayat, Jasmin Giles, Madhurima S Gundlapally and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular ecology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 5 countries.

Noémie BonninSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0001-5529-7452
Alex K PielDepartment of Anthropology, University College London, London, UK.ORCID 0000-0002-4674-537X
Richard P BrownSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0003-2401-6077
Yingying LiDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andrew Jesse ConnellDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9393-3074
Alexa N AvittoDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jean P BoubliSchool of Science, Engineering & Environment, University of Salford, Salford, UK.
Adrienne ChitayatInstitute of Biodiversity and Ecological Dynamics, University of Amsterdam, Amsterdam, The Netherlands.
Jasmin GilesDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Madhurima S GundlapallyDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Iddi LipendeTanzania Wildlife Research Institute (TAWIRI), Arusha, Tanzania.
Elizabeth V LonsdorfDepartment of Psychology, Franklin and Marshall College, Lancaster, Pennsylvania, USA.
Deus MjunguGombe Stream Research Centre, The Jane Goodall Institute-Tanzania, Kigoma, Tanzania.
Dismas MwachaGombe Stream Research Centre, The Jane Goodall Institute-Tanzania, Kigoma, Tanzania.
Lilian PinteaConservation Science Department, The Jane Goodall Institute, Washington, District of Columbia, USA.
Anne E PuseyDepartment of Evolutionary Anthropology, Duke University, Durham, North Carolina, USA.
Jane RaphaelGombe National Park, Kigoma, Tanzania.
Serge A WichSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0003-3954-5174
Michael L WilsonDepartment of Anthropology, University of Minnesota, Minneapolis, Minnesota, USA.
Emily E WroblewskiAnthropology Department, Washington University, St. Louis, Missouri, USA.
Beatrice H HahnDepartments of Medicine and Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-9400-9887
Fiona A StewartSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-4929-4711
University of Pennsylvania · USInstitute for Biodiversity · DELiverpool John Moores University · GBThe Jane Goodall Institute · TZUniversity College London · GBDuke University · USEmory University · USTanzania National Parks · TZTanzania Wildlife Research Institute · TZThe Jane Goodall Institute · USUniversity of Minnesota · USUniversity of Salford · GBWashington University in St. Louis · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DAVID S METZGER · 1999 to 2026
$78.6M
Optimizing glycan shield coverage, germline B cell receptor binding and epitope diversity of V2-apex targeted HIV-1 Env immunogensR37AI150590 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Beatrice H Hahn · 2019 to 2026
$6.9M
Natural SIV Reservoirs and Human Zoonotic RiskR01AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2001 to 2022
$6.1M
Natural SIV Reservoirs and Human Zoonotic RiskR37AI050529 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2008 to 2017
$5.7M
Studies of the precursor of the human AIDS virus in its natural chimpanzee hostR01AI120810 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HAHN, BEATRICE H · 2016 to 2020
$3.4M
NIAID NIH HHS P30 AI045008NIAID NIH HHS R01 AI050529NIAID NIH HHS R01 AI120810NIAID NIH HHS R37 AI050529NIAID NIH HHS R37 AI150590
6 · The paper itself

Abstract

Populations on the edge of a species' distribution may represent an important source of adaptive diversity, yet these populations tend to be more fragmented and are more likely to be geographically isolated. Lack of genetic exchanges between such populations, due to barriers to animal movement, can not only compromise adaptive potential but also lead to the fixation of deleterious alleles. The south-eastern edge of chimpanzee distribution is particularly fragmented, and conflicting hypotheses have been proposed about population connectivity and viability. To address this uncertainty, we generated both mitochondrial and MiSeq-based microsatellite genotypes for 290 individuals ranging across western Tanzania. While shared mitochondrial haplotypes confirmed historical gene flow, our microsatellite analyses revealed two distinct clusters, suggesting two populations currently isolated from one another. However, we found evidence of high levels of gene flow maintained within each of these clusters, one of which covers an 18,000 km

Indexed as

Genetics, PopulationGenetic VariationAnimalsEcosystemGene FlowHaplotypesMicrosatellite RepeatsPan troglodytesbiogeographygenetic diversitygreat apesmicrosatellitesmitochondrial DNATanzania

Identifiers

PMID37277946
PMCPMC10421595
OpenAlexW4379508805

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.