Evidence map›Paper›PMID 37277781›Full record

ArticleBMC public health2023

Resurgence of influenza and respiratory syncytial virus in Egypt following two years of decline during the COVID-19 pandemic: outpatient clinic survey of infants and children, October 2022.

Amr Kandeel, Manal Fahim, Ola Deghedy, Wael H Roshdy, Mohamed K Khalifa, Rabeh El Shesheny, Ahmed Kandeil, Amel Naguib, Salma Afifi, Amira Mohsen and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. [Epidemiology, Mechanisms, and Clinical Challenges of Respiratory Syncytial Virus Co-infections in Children].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Childhood infectious diseases: experiences and challenges.World journal of pediatrics : WJP · 2025
    Article
  13. Observational
  14. Article
  15. Investigating DNA damage caused by COVID-19 and influenza in post COVID-19.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Amr KandeelMinistry of Health and Population, Cairo, Egypt.
Manal FahimMinistry of Health and Population, Cairo, Egypt.
Ola DeghedyMinistry of Health and Population, Cairo, Egypt.
Wael H RoshdyCentral Public Health Laboratory, Ministry of Health and Population, Cairo, Egypt.
Mohamed K KhalifaCentre of Scientific Excellence for Influenza Viruses, National Research Centre, 12622, Dokki, Giza, Egypt.
Rabeh El SheshenyCentre of Scientific Excellence for Influenza Viruses, National Research Centre, 12622, Dokki, Giza, Egypt.
Ahmed KandeilCentre of Scientific Excellence for Influenza Viruses, National Research Centre, 12622, Dokki, Giza, Egypt.
Amel NaguibCentral Public Health Laboratory, Ministry of Health and Population, Cairo, Egypt.
Salma AfifiConsultant Ministry of Health and Population, Cairo, Egypt.
Amira MohsenNational Research Center, Cairo, Egypt.
Khaled AbdelghaffarMinistry of Health and Population, Cairo, Egypt.
Ministry of Health and Population · EGNational Research Centre · EGNational Water Research Center · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTwo years after unprecedented low rates of circulation of most common respiratory viruses (SARS-CoV-2), the Egyptian ARI surveillance system detected an increase in acute respiratory infections (ARIs) with a reduced circulation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially among school children. A national survey was conducted to estimate the burden and identify the viral causes of ARIs among children < 16 years of age.

methodsA one-day survey was carried out in 98 governmental outpatient clinics distributed all over Egypt 26 governorates. The four largest referral hospitals in each governorate where most influenza-like illness (ILI) patients seek care were selected. Using the WHO case definition, the first five patients < 16 years of age with ILI symptoms visiting the selected outpatient clinics on the survey day were enrolled. Basic demographic and clinical data of patients were collected using a linelist. Patients were swabbed and tested for SARS-CoV-2, influenza, and Respiratory Syncytial virus (RSV) by RT-PCR at the Central Laboratory in Cairo.

resultsOverall, 530 patients enrolled, their mean age was 5.8 ± 4.2, 57.1% were males, and 70.2% reside in rural or semi-rural areas. Of all patients, 134 (25.3%) had influenza, 111 (20.9%) RSV, and 14 (2.8%) coinfections. Influenza-positive children were older compared to RSV, (7.2 ± 4.1, 4.3 ± 4.1, p < 0.001), with more than half of them (53.0%) being school students. Dyspnea was reported in RSV more than in influenza (62.2% vs. 49.3%, p < 0.05). Among RSV patients, children < 2 years had a higher rate of dyspnea than others (86.7% vs. 53.1%, < 0.001).

conclusionsA resurgence of influenza and RSV was detected in Egypt in the 2022-2023 winter season. Influenza caused a higher rate of infection than RSV, while RSV caused more severe symptoms than influenza. Monitoring a broader range of respiratory pathogens is recommended to estimate the ARI burden and risky groups for severe disease in Egypt.

Indexed as

COVID-19Influenza, HumanRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsVirus DiseasesChildEgyptFemaleHumansInfantMalePandemicsSARS-CoV-2Acute respiratory infectionInfluenza virusesOutbreakRespiratory Syncytial virusSurvey

Identifiers

PMID37277781
PMCPMC10240446
OpenAlexW4379467445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.