Evidence map›Paper›PMID 37277752›Full record

ArticleBMC public health2023

Lead (Pb) and cadmium (Cd) blood levels and potential hematological health risk among inhabitants of the claimed hazardous region around Qaroun Lake in Egypt.

Salwa Bakr, Makram Ahmed Sayed, Karem Mohamed Salem, Enas Mohamed Morsi, Mohamed Masoud, Eman Mahmoud Ezzat

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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  2. cGAS-STING signaling in pollution-induced toxicity: mechanism and relieving medication.Apoptosis : an international journal on programmed cell death · 2026
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  6. Development and validation of an ICP-MS method and its application in assessing heavy metals in whole blood samples among occupationally exposed lead smelting plant workers.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Salwa BakrDepartment of Clinical Pathology/ Hematology & Transfusion Medicine, Faculty of Medicine, Fayoum University, P.O Box: 63514, Fayoum, Egypt. salwabakr1@hotmail.com.
Makram Ahmed SayedHead of Environmental and Food Pollutants Analysis Lab, Faculty of Agriculture, Fayoum University, Fayoum, Egypt.
Karem Mohamed SalemDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Enas Mohamed MorsiDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Mohamed MasoudDepartment of Public Health and Community Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Eman Mahmoud EzzatDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Fayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLead (Pb) and cadmium (Cd) heavy metals are considered potentially hazardous toxins which cause serious health problems. Many studies reported that the water of Qaroun Lake in Fayoum, Egypt with its fish farms was contaminated with Pb and Cd above permissible levels. However, there is a lack of studies addressing levels of these toxic metals among inhabitants.

objectivesWe aimed to evaluate blood levels of Pb and Cd and their potential health risk among inhabitants around Qaroun Lake. MATERIALS AND

methodsThis case-control study estimated Pb and Cd blood levels among 190 individuals from two destinations (near and far away) of Qaroun Lack using an atomic absorption spectrometer after full history taking and routine checkup investigations; Full blood count, serum ferritin, liver enzyme (ALT), and creatinine levels.

resultsThere was a significant difference between blood levels of Pb and Cd heavy metals of inhabitants from near and far away Qaroun Lake destinations (p-value < 0.001). The majority of inhabitants around Qaroun Lake had Pb and Cd blood levels above permissible levels (100% and 60% respectively). Critical levels out of them were 12.1% and 30.3% respectively. In comparison to inhabitants faraway Qaroun Lake, three individuals (2.4%) had Cd above the permissible level, while all of them (100%) had Pb level within the permissible level. There were no statistically significant differences between the two sampled populations as regards hemoglobin level, ALT, creatinine, and ferritin serum levels (p-value > 0.05). The difference between studied populations regarding types of anemia was not statistically significant. Subclinical leucopenia was higher in the population near Qaroun Lake when compare to inhabitants far from the lake (13.6% vs. 4.8%, p-value 0.032).

conclusionBio-monitoring of populations exposed to Pb and Cd hazardous substances could help in generating an early warning system to reduce the disease burden associated with their toxicity.

Indexed as

Metals, HeavyWater Pollutants, ChemicalCadmiumCase-Control StudiesCreatinineEgyptEnvironmental MonitoringFerritinsHumansLakesLeadRisk AssessmentCadmiumCreatinineFerritinsLeadMetals, HeavyWater Pollutants, ChemicalCadmiumEgyptLeadQarounWadi El-Rayan

Identifiers

PMID37277752
PMCPMC10240759
OpenAlexW4379472878

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.