Evidence map›Paper›PMID 37277716›Full record

ArticleBMC ophthalmology2023

Increased METTL3 expression and m

Jun Ma, Xiaotang Wang, Xue Yang, Xi Wang, Tongshan Tan, Hongping Fang, Yu Zhong, Qi Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Methyltransferase-like 3-mediated RNA NFrontiers in immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jun Ma *The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaotang Wang *The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xue YangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xi WangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tongshan TanThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Hongping FangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yu ZhongDepartment of Combination of Chinese and Western Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. yuyumou@sina.com.
Qi ZhangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China. cqzqwxm@163.com.
Chongqing Medical University · CNNational Clinical Research Center for Digestive Diseases · CNFirst Affiliated Hospital of Chongqing Medical University · CN

Funding

Joint Medical Research Project of Chongqing Health Commission and Science and Technology Bureau 2019MSXM003National Natural Science Foundation Project 82070935Natural Science Foundation Project of Chongqing cstc2019jcyj-msxmX0398
6 · The paper itself

Abstract

backgroundPrimary Sjögren's syndrome (pSS) is a chronic autoimmune disorder defined by xerostomia and keratoconjunctivitis sicca, and its etiology remains unknown. N6-methyladenosine (m

methodsThis cross-sectional study included forty-eight pSS patients with dry eye and forty healthy controls (HCs). Peripheral blood mononuclear cells (PBMCs) were isolated, and the level of m

resultsThe expression level of m

conclusionsOur work revealed that the upregulation of m

Indexed as

Dry Eye SyndromesSjogren's SyndromeCross-Sectional StudiesHumansLeukocytes, MononuclearMethylationMethyltransferasesRNAMethyltransferasesMETTL3 protein, humanRNADry eyeMETTL3N6-methyladenosinePrimary Sjögren’s syndrome

Identifiers

PMID37277716
PMCPMC10243060
OpenAlexW4379471919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.