Evidence map›Paper›PMID 37277703›Full record

Trial reportBMC anesthesiology2023

The effect of erector spinae plane block on fentanyl consumption during open abdominal hysterectomy: a randomised controlled study.

Mohamed Ahmed Hamed, Maged Labib Boules, Mohamed Abd El Moniem Mahmoud, Rana Ahmed Abdelghaffar

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05072184 nacompletednot on this map

the Effect of Erector Spinae Plane Block on Fentanyl Consumption During Abdominal Hysterectomy

TypeinterventionalSponsorFayoum University HospitalRan2021 to 2022Enrolled100ConditionsPost Operative PainArmsESP block
NCT07178262 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Opioid Sparing Effect of Erector Spinae Block in Patients Undergoing Total Abdominal Hysterectomy; A Randomized Control Trial

TypeinterventionalSponsorKulsoom International HospitalRan2025 to 2025Enrolled60ConditionsErector Spinae Block, Enhanced Recovery After Surgery (ERAS) Protocol, OpioidArmsErector Spinae (ESP) Block with Bupivacaine (Marcaine®), Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohamed Ahmed HamedDepartment of Anesthesiology, Faculty of Medicine, Fayoum University, Fayoum, 63511, Egypt. mah07@fayoum.edu.eg.
Maged Labib BoulesDepartment of Anesthesiology, Faculty of Medicine, Fayoum University, Fayoum, 63511, Egypt.
Mohamed Abd El Moniem MahmoudDepartment of Anesthesiology, Faculty of Medicine, Fayoum University, Fayoum, 63511, Egypt.
Rana Ahmed AbdelghaffarDepartment of Anesthesiology, Faculty of Medicine, Fayoum University, Fayoum, 63511, Egypt.
Fayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative analgesia is very important during an abdominal hysterectomy. Determining the impact of the erector spinae plane block (ESPB) on patients undergoing an open abdominal hysterectomy while under general anesthesia was our aim.

methodsIn order to create equal groups, 100 patients who underwent elective open abdominal hysterectomies under general anesthesia were enlisted. The preoperative bilateral ESPB with 20 ml of bupivacaine 0.25% was administered to the ESPB group (n = 50). The same procedure was performed on the control group (n = 50), but they received a 20-ml saline injection instead. The primary outcome is the total amount of fentanyl consumed during surgery.

resultsWe found that the mean (SD) intraoperative fentanyl consumption was significantly lower in the ESPB group than in the control group (82.9 (27.4) g vs. 148.5 (44.8) g, with a 95% CI = -80.3 to -50.8; p 0.001). Likewise, mean (SD) postoperative fentanyl consumption was significantly lower in the ESPB group than in the control group (442.4 (17.8) g vs. 477.9 (10.4) g, with a 95% CI = -41.3 to -29.7; p 0.001). On the other hand, there is no statistically significant difference between the two study groups regarding sevoflurane consumption (89.2 (19.5) ml vs. 92.4 (15.3) ml, with a 95% CI = -10.1 to 3.8; p 0.4). We documented that during the post-operative period (0-24 h), VAS scores at rest were, on average, 1.03 units lower in the ESPB group (estimate = -1.03, 95% CI = -1.16-(-0.86), t = -14.9, p-value 0.001), and VAS scores during cough were, on average, 1.07 units lower in the ESPB group (estimate = -1.07, 95% CI = -1.21-(-0.93), t = -14.8, p-value 0.001).

conclusionBilateral ESPB can be utilized as an adjuvant method to reduce intraoperative fentanyl consumption and enhance postoperative pain control in patients undergoing open total abdominal hysterectomy under general anesthesia. It is effective, secure, and little obtrusive.

trial registrationNo protocol revisions or study amendments have been made since the trial's inception, according to the information on ClinicalTrials.gov (NCT05072184; principal investigator: Mohamed Ahmed Hamed; date of registration: October 28, 2021).

Indexed as

Nerve BlockResearch DesignAnesthesia, GeneralFemaleFentanylHumansHysterectomyPostoperative PainUltrasonography, InterventionalFentanylAbdominal hysterectomyErector spinae plane blockFentanyl consumptionPostoperative pain

Identifiers

PMID37277703
PMCPMC10240679
OpenAlexW4379470217

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.