Evidence map›Paper›PMID 37277539›Full record

ArticleMedical microbiology and immunology2023

Picking up speed: cell cycle regulation during effector CD8

Lorenz Kretschmer, Noémie Fuchs, Dirk H Busch, Veit R Buchholz

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Medical microbiology and immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lorenz KretschmerInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany. lorenz.kretschmer@tum.de.
Noémie FuchsInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Dirk H BuschInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Veit R BuchholzInstitute for Medical Microbiology, Immunology and Hygiene, Technische Universität München (TUM), Munich, Germany.
Institute of Medical Microbiology and Hygiene · DEGerman Center for Infection Research · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clonal expansion and development of immunological memory are two hallmarks of adaptive immune responses. Resolving the intricate pathways that regulate cell cycle activity and lead to the generation of diverse effector and memory T cell subsets is essential for improving our understanding of protective T cell immunity. A deeper knowledge of cell cycle regulation in T cells also has translational implications for adoptive cell therapies and vaccinations against infectious diseases. Here, we summarize recent evidence for an early diversification of effector and memory CD8

Indexed as

CD8-Positive T-LymphocytesT-Lymphocyte SubsetsCell CycleCell DifferentiationImmunologic MemoryLymphocyte ActivationCD8+ T cellsCell cycleClonal expansionImmunological memorySingle cell fate mappingT cell memory

Identifiers

PMID37277539
PMCPMC10293348
OpenAlexW4379374900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.