Evidence map›Paper›PMID 37277512›Full record

ArticleScientific reports2023

Chemical composition of extracts from leaves, stems and roots of wasabi (Eutrema japonicum) and their anti-cancer, anti-inflammatory and anti-microbial activities.

Katarzyna Dos Santos Szewczyk, Weronika Skowrońska, Aleksandra Kruk, Anna Makuch-Kocka, Anna Bogucka-Kocka, Małgorzata Miazga-Karska, Anna Grzywa-Celińska, Sebastian Granica

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Immunomodulatory Effects and Regulatory Mechanisms of (Journal of agricultural and food chemistry · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katarzyna Dos Santos SzewczykDepartment of Pharmaceutical Botany, Medical University of Lublin, Chodźki 1, 20-093, Lublin, Poland. k.szewczyk@umlub.pl.
Weronika SkowrońskaDepartment of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Banacha 1 Street, 02-097, Warsaw, Poland.
Aleksandra KrukDepartment of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Banacha 1 Street, 02-097, Warsaw, Poland.
Anna Makuch-KockaDepartment of Pharmacology, Medical University of Lublin, Radziwiłłowska 11, 20-080, Lublin, Poland.
Anna Bogucka-KockaDepartment of Biology and Genetics, Medical University of Lublin, Chodźki 4a, 20-093, Lublin, Poland.
Małgorzata Miazga-KarskaDepartment of Biochemistry and Biotechnology, Medical University of Lublin, Chodźki 1, 20-093, Lublin, Poland.
Anna Grzywa-CelińskaChair and Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090, Lublin, Poland.
Sebastian GranicaMicrobiota Lab, Department of Pharmacognosy and Molecular Basis of Phytotherapy, Faculty of Pharmacy Medical, Centre for Preclinical Research, University of Warsaw, Banacha 1 Street, 02-097, Warsaw, Poland. sgranica@wum.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of our study was to evaluate the composition of the extracts obtained from the roots and leaves of Eutrema japonicum cultivated in Poland. For this purpose, LC-DAD-IT-MS and LC-Q-TOF-MS analyses were used. The results revealed the presence of forty-two constituents comprising glycosinolates, phenylpropanoid glycosides, flavone glycosides, hydroxycinnamic acids, and other compounds. Then, the resultant extracts were subjected to an assessment of the potential cytotoxic effect on human colon adenocarcinoma cells, the effect on the growth of probiotic and intestinal pathogenic strains, as well as their anti-inflammatory activity. It was demonstrated that 60% ethanol extract from the biennial roots (WR2) had the strongest anti-inflammatory, antibacterial, and cytotoxic activities compared to the other samples. Our results suggest that extracts from E. japonicum may be considered as a promising compound for the production of health-promoting supplements.

Indexed as

AdenocarcinomaColonic NeoplasmsWasabiaAnti-Inflammatory AgentsGlycosidesHumansPlant ExtractsPlant LeavesAnti-Inflammatory AgentsGlycosidesPlant Extracts

Identifiers

PMID37277512
PMCPMC10241793

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.