ReviewNature reviews. Nephrology2023
Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges.
Review in Nature reviews. Nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 77 citations in OpenAlex.
- Nephrology 2050: an evidence-informed roadmap from precision prevention to kidney regeneration.International urology and nephrology · 2026Review
- Research Progress and Critical Challenges of Bioartificial Kidneys in Renal Replacement Therapy for End-Stage Renal Disease.Biomolecules · 2026Review
- Modelling and Experimental Study of Low Flow Rate Miniaturized Electrodialysis for Artificial Kidney Applications.Journal of applied physics · 2026Article
- Removal of Protein-Bound Uremic Toxins by Mixed Matrix Membranes of Cellulose Acetate/Silica/MOF.Membranes · 2026Article
- Kidney health for all: caring for people, protecting the planet.Kidney medicine · 2026Article
- An In Vitro System for Studying Toxin Transport Across Hemodialysis Membranes.Artificial organs · 2026Article
- A website calculator to benchmark the carbon footprint of haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Article
- Advancing green nephrology: a scoping review of sustainability interventions in kidney care.International urology and nephrology · 2026Article
- Kidney health for all: Caring for people, protecting the planet.Journal of family medicine and primary care · 2026Article
- Decoding High-voltage LiCoOAdvanced materials (Deerfield Beach, Fla.) · 2026Review
- Kidney health for all: caring for people, protecting the planet.Kidney international reports · 2026Article
- Kidney Health for all: Caring for People, Protecting the Planet.Canadian journal of kidney health and disease · 2026Article
- A guide to uraemic toxicity.Nature reviews. Nephrology · 2026Review
- From Dialysis to Destinations: Safe Travel Strategies for Patients With CKD.Kidney international reports · 2025Review
- Microfluidic technologies for wearable and implantable biomedical devices.Lab on a chip · 2025Review
- Functional Carbon-Based Materials for Blood Purification: Recent Advances Toward Improved Treatment of Renal Failure and Patient Quality of Life.Bioengineering (Basel, Switzerland) · 2025Review
- Living with chronic kidney disease: future perspectives and prognostic needs of patients - a qualitative study.BMC nephrology · 2025Article
- Contemporary Perspectives on Chronic Renal Disorders.Chronic diseases and translational medicine · 2025Review
- 2023 European Kidney Forum: The future of kidney care - investing in green nephrology to meet the European Green Deal targets.Journal of nephrology · 2025Article
- Preclinical approaches in regenerative medicine for treating end-stage renal disease: a scoping review.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haemodialysis is life sustaining but expensive, provides limited removal of uraemic solutes, is associated with poor patient quality of life and has a large carbon footprint. Innovative dialysis technologies such as portable, wearable and implantable artificial kidney systems are being developed with the aim of addressing these issues and improving patient care. An important challenge for these technologies is the need for continuous regeneration of a small volume of dialysate. Dialysate recycling systems based on sorbents have great potential for such regeneration. Novel dialysis membranes composed of polymeric or inorganic materials are being developed to improve the removal of a broad range of uraemic toxins, with low levels of membrane fouling compared with currently available synthetic membranes. To achieve more complete therapy and provide important biological functions, these novel membranes could be combined with bioartificial kidneys, which consist of artificial membranes combined with kidney cells. Implementation of these systems will require robust cell sourcing; cell culture facilities annexed to dialysis centres; large-scale, low-cost production; and quality control measures. These challenges are not trivial, and global initiatives involving all relevant stakeholders, including academics, industrialists, medical professionals and patients with kidney disease, are required to achieve important technological breakthroughs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.