Evidence map›Paper›PMID 37277327›Full record

ArticleNature communications2023

Hamster model for post-COVID-19 alveolar regeneration offers an opportunity to understand post-acute sequelae of SARS-CoV-2.

Laura Heydemann, Małgorzata Ciurkiewicz, Georg Beythien, Kathrin Becker, Klaus Schughart, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou-Kouassi, Sebastian Beck, Martin Zickler and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  5. Long COVID: current research and future directions.Infectious diseases & immunity · 2025
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  12. Animal models of Long Covid: A hit-and-run disease.Science translational medicine · 2024
    Review
  13. Article
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  15. Article
  16. Article
  17. SARS-CoV-2 immunity in animal models.Cellular & molecular immunology · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Laura Heydemann *Department of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.ORCID 0000-0002-9958-4872
Małgorzata Ciurkiewicz *Department of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.ORCID 0000-0001-6277-7366
Georg BeythienDepartment of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.ORCID 0000-0002-2192-2413
Kathrin BeckerDepartment of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.ORCID 0000-0002-0922-8189
Klaus SchughartDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, Tennessee, USA.ORCID 0000-0002-6824-7523
Stephanie Stanelle-BertramDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Berfin SchaumburgDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Nancy Mounogou-KouassiDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Sebastian BeckDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Martin ZicklerDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Mark KühnelInstitute of Pathology, Hannover Medical School (MHH), Hannover, Germany.
Gülsah GabrielDepartment for Viral Zoonoses-One Health, Leibniz Institute for Virology, Hamburg, Germany.
Andreas BeinekeDepartment of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.
Wolfgang Baumgärtner *Department of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany. Wolfgang.baumgaertner@tiho-hannover.de.ORCID 0000-0001-8151-5644
Federico Armando *Department of Pathology, University of Veterinary Medicine, Foundation, Hannover, Germany.ORCID 0000-0002-2578-4409
University of Veterinary Medicine Hannover, Foundation · DEMedizinische Hochschule Hannover · DEUniversity of Tennessee Health Science Center · US

Funding

Unlocking Zika Virus Immune Control and Pathogenesis with the Collaborative CrossU19AI100625 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MCWEENEY, SHANNON K. · 2012 to 2021
$36.6M
NIAID NIH HHS U19 AI100625
6 · The paper itself

Abstract

COVID-19 survivors often suffer from post-acute sequelae of SARS-CoV-2 infection (PASC). Current evidence suggests dysregulated alveolar regeneration as a possible explanation for respiratory PASC, which deserves further investigation in a suitable animal model. This study investigates morphological, phenotypical and transcriptomic features of alveolar regeneration in SARS-CoV-2 infected Syrian golden hamsters. We demonstrate that CK8

Indexed as

COVID-19SARS-CoV-2Alveolar Epithelial CellsAnimalsCell DifferentiationCricetinaeDisease ProgressionHumansMesocricetusPost-Acute COVID-19 Syndrome

Identifiers

PMID37277327
PMCPMC10241385
OpenAlexW4379470096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.