Evidence map›Paper›PMID 37277225›Full record

ArticleBMJ open diabetes research & care2023

Strains of

John Kallassy, Emily Gagnon, Dawn Rosenberg, Lawrence K Silbart, Simon A McManus

Open access · goldAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Improving Growth Dynamics ofInternational journal of molecular sciences · 2026
    Article
  3. Gut microbes · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Probiotics in reducing obesity by reconfiguring the gut microbiota.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

John KallassyBactana Corp, Farmington, Connecticut, USA.
Emily GagnonBactana Corp, Farmington, Connecticut, USA.
Dawn RosenbergBactana Corp, Farmington, Connecticut, USA.
Lawrence K SilbartDepartment of Allied Health Sciences, University of Connecticut, Storrs, Connecticut, USA.
Simon A McManusBactana Corp, Farmington, Connecticut, USA simon@bactana.com.ORCID 0000-0003-1714-1259
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe commensal bacterium RESEARCH DESIGN AND

methodsThe aim of this study was to investigate the effects of compositions derived from three strains of

resultsBoth trials in prediabetic and diabetic mice revealed that peroral administration of live FPZ or extracts from FPZ lowered fasting blood glucose levels and improved glucose tolerance compared with control mice. A trial administering longer FPZ treatment also resulted in lowered percent HbA1c compared with control mice. Additionally, trials in non-diabetic mice treated with FPZ demonstrated that FPZ treatment does not lead to hypoglycemia.

conclusionsThe trial results have shown that treatment with different formulations of FPZ result in lower blood glucose levels, lower percent HbA1c, and improved glucose response in mice compared with control prediabetic/diabetic mice. FPZ is a promising candidate as an orally administered probiotic or postbiotic to manage and improve pre-diabetes and T2D.

Indexed as

Diabetes Mellitus, Type 2Major Depressive DisorderPrediabetic StateAnimalsBlood GlucoseFaecalibacterium prausnitziiGlycated HemoglobinHumansHypoglycemic AgentsMaleMiceMice, Inbred C57BLObesityBlood GlucoseGlycated HemoglobinHypoglycemic AgentsGlucose Tolerance TestGlycated Hemoglobin AHypoglycemiaPrediabetic State

Identifiers

PMID37277225
PMCPMC10254995
OpenAlexW4379469060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.