Evidence map›Paper›PMID 37277211›Full record

ArticleRMD open2023

Characterisation of patients with axial psoriatic arthritis and patients with axial spondyloarthritis and concomitant psoriasis in the SCQM registry.

Adrian Ciurea, Andrea Götschi, Seraphina Kissling, Alexander Bernatschek, Kristina Bürki, Pascale Exer, Michael J Nissen, Burkhard Möller, Almut Scherer, Raphael Micheroli

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Adrian CiureaDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland adrian.ciurea@usz.ch.ORCID 0000-0002-7870-7132
Andrea GötschiDataScience, Swiss Clinical Quality Management in Rheumatic Diseases, Zurich, Switzerland.
Seraphina KisslingDataScience, Swiss Clinical Quality Management in Rheumatic Diseases, Zurich, Switzerland.
Alexander BernatschekDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Kristina BürkiDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Pascale ExerPraxis Rheuma-Basel, Basel, Switzerland.
Michael J NissenDepartment of Rheumatology, Geneva University Hospitals, Geneva, Switzerland.ORCID 0000-0002-6326-1764
Burkhard MöllerDepartment of Rheumatology and Immunology, University Hospital Bern, Bern, Switzerland.
Almut SchererDataScience, Swiss Clinical Quality Management in Rheumatic Diseases, Zurich, Switzerland.
Raphael MicheroliDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-8918-7304
University of Zurich · CHSCQM Foundation · CHUniversity Hospital of Bern · CHUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWithin the spectrum of spondyloarthritides, axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) present with overlapping features. Axial involvement in PsA (axial PsA) is treated according to recommendations for axSpA, as specific studies in axial PsA are scarce. We compared characteristics of patients with axSpA (particularly of patients with axSpA and concomitant psoriasis (pso)) with those of patients with axial PsA.

methodsPatients with axSpA and PsA in the Swiss Clinical Quality Management (SCQM) registry were included if information on pso and axial involvement was available. Patients with AxSpA were stratified by axSpA with and without pso (axSpA±pso) and patients with PsA were stratified to axial PsA or strictly peripheral PsA.

resultsPrevious or current psoriasis was observed in 479/4489 patients with axSpA (10.7%). Of 2631 patients with PsA, 1153 (43.8%) presented with axial involvement (opinion of the treating rheumatologist). Compared with patients with axSpA+pso, patients with axial PsA were older at symptom onset and at inclusion in SCQM, were less frequently HLA-B27 positive, had back pain less frequently and a higher prevalence of dactylitis and peripheral arthritis. A positive family history of pso or PsA was more frequent in axial PsA, while a positive family history of axSpA was more frequent in patients with axSpA+pso. Disease activity, function and mobility were comparable in axSpA+pso versus axial PsA.

conclusionPatients with axial PsA differ from patients with axSpA+pso in important demographic and clinical characteristics, and genetically, but present with a comparable disease burden. Treatment studies specifically dedicated to axial PsA seem warranted.

Indexed as

Arthritis, PsoriaticAxial SpondyloarthritisPsoriasisSpondylarthritisHumansRegistriesArthritis, PsoriaticEpidemiologySpondylitis, Ankylosing

Identifiers

PMID37277211
PMCPMC10254714
OpenAlexW4379377647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.