ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023
Behavioral State-Dependent Modulation of Prefrontal Cortex Activity by Respiration.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- From Breath to Behavior: Respiratory Features Predict Visual Detection Performance.bioRxiv : the preprint server for biology · 2026Article
- It's About Time-Breathing Dynamics Modulate Emotion and Cognition.Psychophysiology · 2025Article
- Global coordination of brain activity by the breathing cycle.Nature reviews. Neuroscience · 2025Review
- Breathing Modulates Network Activity in Frontal Brain Regions during Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- [Neuronal plasticity changes in the central amygdala and prelimbic cortex network in mice with chronic unpredictable mild stress-induced depression].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- A persistent prefrontal reference frame across time and task rules.Nature communications · 2024Article
- Oscillatory Waveform Shape and Temporal Spike Correlations Differ across Bat Frontal and Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Respiratory Coupled Oscillations as a Mechanism of Attention to the Olfactory Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neuronal tuning to threat exposure remains stable in the mouse prefrontal cortex over multiple days.PLoS biology · 2024Article
- Low- and high-level coordination of orofacial motor actions.Current opinion in neurobiology · 2023Review
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Respiration-rhythmic oscillations in the local field potential emerge in the mPFC, a cortical region with a key role in the regulation of cognitive and emotional behavior. Respiration-driven rhythms coordinate local activity by entraining fast γ oscillations as well as single-unit discharges. To what extent respiration entrainment differently engages the mPFC network in a behavioral state-dependent manner, however, is not known. Here, we compared the respiration entrainment of mouse PFC local field potential and spiking activity (23 male and 2 female mice) across distinct behavioral states: during awake immobility in the home cage (HC), during passive coping in response to inescapable stress under tail suspension (TS), and during reward consumption (Rew). Respiration-driven rhythms emerged during all three states. However, prefrontal γ oscillations were more strongly entrained by respiration during HC than TS or Rew. Moreover, neuronal spikes of putative pyramidal cells and putative interneurons showed significant respiration phase-coupling throughout behaviors with characteristic phase preferences depending on the behavioral state. Finally, while phase-coupling dominated in deep layers in HC and Rew conditions, TS resulted in the recruitment of superficial layer neurons to respiration. These results jointly suggest that respiration dynamically entrains prefrontal neuronal activity depending on the behavioral state.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.