ArticleJournal of biomechanics2023
Unilateral transfemoral osseointegrated prostheses improve joint loading during walking.
Article in Journal of biomechanics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- [Transcutaneous osseointegration for amputees: foundational principles and current concepts].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Simulated gait training improves joint loading symmetry in unilateral transfemoral bone-anchored limb users.Journal of biomechanics · 2026Article
- Feasibility of predicting changes in gait biomechanics following muscle strength perturbations using optimal control in patients with transfemoral amputation.Computer methods in biomechanics and biomedical engineering · 2026Article
- Whole-body angular momentum is influenced by bone-anchored limb use and amputation level during walking.Gait & posture · 2026Article
- Hip joint mechanics during swing limb advancement with bone-anchored limb use.Journal of biomechanics · 2025Observational
- Increased loading of the lateral knee compartment in the unamputated knee during gait in people with unilateral transfemoral/through-knee amputations.Bone & joint research · 2025Article
- CORR Insights®: Associations Between Skeletal Alignment and Biomechanical Symmetry Before and After Transfemoral Bone-anchored Limb Implantation.Clinical orthopaedics and related research · 2025Article
- Associations Between Skeletal Alignment and Biomechanical Symmetry Before and After Transfemoral Bone-anchored Limb Implantation.Clinical orthopaedics and related research · 2025Article
- Transfemoral bone-anchored limb use changes dynamic hip muscle forces during walking.Journal of biomechanics · 2025Article
- Altered cumulative joint moments and increased joint moment symmetry during sit-to-stand transitions for transfemoral bone-anchored limb users: A case series.Clinical biomechanics (Bristol, Avon) · 2025Article
- Estimating temporal bone-implant stresses in patients with bone-anchored lower limbs.Journal of biomechanics · 2025Article
- Evidence-based recommendation of a powered knee for transfemoral bone-anchored prostheses: A cross-sectional study.Canadian prosthetics & orthotics journal · 2025Article
- A one-year follow-up case series on gait analysis and patient-reported outcomes for persons with unilateral and bilateral transfemoral amputations undergoing direct skeletal fixation.Journal of neuroengineering and rehabilitation · 2024Article
- Cumulative loading increases and loading asymmetries persist during walking for people with a transfemoral bone-anchored limb.Gait & posture · 2024Article
- The biomechanical influence of transtibial Bone-Anchored limbs during walking.Journal of biomechanics · 2024Article
- Recent Advances in Biomimetics for the Development of Bio-Inspired Prosthetic Limbs.Biomimetics (Basel, Switzerland) · 2024Review
- Lumbopelvic movement coordination during walking improves with transfemoral bone anchored limbs: Implications for low back pain.Gait & posture · 2024Observational
- The Amputated Limb Gluteus Medius is Biomechanically Disadvantaged in Patients with Unilateral Transfemoral Amputation.Annals of biomedical engineering · 2024Article
- Hip joint and muscle loading for persons with bilateral transfemoral/through-knee amputations: biomechanical differences between full-length articulated and foreshortened non-articulated prostheses.Journal of neuroengineering and rehabilitation · 2023Article
- Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives.Current oncology reports · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
People with unilateral transfemoral amputation using socket prostheses are at increased risk for developing osteoarthritis in both the residual hip and intact lower-limb joints. Osseointegrated prostheses are a surgical alternative to socket prostheses that directly attach to the residual femur via a bone-anchored implant, however their multi-joint loading effect is largely unknown. Our objective was to establish how osseointegrated prostheses influence joint loading during walking. Motion capture data (kinematics, ground reaction forces) were collected from 12 participants at baseline, with socket prostheses, and 12-months after prosthesis osseointegration during overground walking at self-selected speeds. Subject-specific musculoskeletal models were developed at each timepoint relative to osseointegration. Internal joint moments were calculated using inverse dynamics, muscle and joint reaction forces (JRFs) were estimated with static optimization. Changes in internal joint moments, JRFs, and joint loading-symmetry were compared using statistical parametric mapping (p≤ 0.05) before and after osseointegration. Amputated limb hip flexion moments and anterior JRFs decreased during terminal stance (p = 0.002, <0.001; respectively), while amputated limb hip abduction moments increased during mid-stance (p < 0.001), amputated hip rotation moment changed from internal to external throughout early stance (p < 0.001). Intact limb hip extension and knee flexion moments (p = 0.028, 0.032; respectively), superior and resultant knee JRFs (p = 0.046, 0.049; respectively) decreased during the loading response following prosthesis osseointegration. These results may indicate that the direct loading transmission of these novel prostheses create a more typical mechanical environment in bilateral joints, which is comparable with loading observed in able-bodied individuals and could decrease the risk of development or progression of osteoarthritis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.