Evidence map›Paper›PMID 37276647›Full record

ArticlePsychiatry research2023

Analysis of symptom clusters amongst adults with anorexia nervosa: Key severity indicators.

Zhuo Li, Jenni Leppanen, Jessica Webb, Philippa Croft, Sarah Byford, Kate Tchanturia

Abstract read
In one paragraph

Article in Psychiatry research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhuo LiKing's College London, London, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, UK.
Jenni LeppanenDepartment of Neuroimaging, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, UK.
Jessica WebbNational Eating Disorders Service, South London and Maudsley NHS Foundation Trust, London, UK.
Philippa CroftNational Eating Disorders Service, South London and Maudsley NHS Foundation Trust, London, UK.
Sarah ByfordKing's Health Economics, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Kate TchanturiaKing's College London, London, Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, UK; National Eating Disorders Service, South London and Maudsley NHS Foundation Trust, London, UK; Psychological Set Research and Correction Center, Tbilisi State Medical University, Tbilisi, Georgia. Electronic address: kate.tchanturia@kcl.ac.uk.

Funding

Medical Research Council MR/R004595/1Wellcome Trust 213,578/Z/18/Z
6 · The paper itself

Abstract

This study used cluster analysis to explore clinically relevant subgroups of adult patients with anorexia nervosa (AN). Patients were clustered based on their body mass index (BMI), eating disorder symptomatology, anxiety and depression symptoms and autistic characteristics. The difference between clusters in work and social functioning, duration of illness, bingeing and purging behaviour, previous hospitalisations and number of comorbidities was also investigated. Two meaningful clusters emerged: a higher symptoms cluster with more severe eating pathology, anxiety, depression, and more autistic traits, and a second cluster with lower symptoms. BMI did not make major contributions to cluster formation. The higher symptoms cluster also reported lower self-efficacy to change, more previous hospitalisations, comorbid diagnoses, binge eating and purging behaviours and use of psychotropic medication. Our findings suggest that weight alone may not be a significant severity indicator amongst inpatients with AN, and targeted treatment of AN should consider a broader range of symptom severity indicators.

Indexed as

Anorexia NervosaBinge-Eating DisorderBulimiaFeeding and Eating DisordersAdultHumansSyndromeAnorexia nervosaAnxietyAutismCluster analysisDepressionEating disorder

Identifiers

PMID37276647
PMCPMC10790244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.