Evidence map›Paper›PMID 37276403›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity.

Jaimie M Mayner, Evan M Masutani, Elena Demeester, Aditya Kumar, Gail Macapugay, Pranjali Beri, Valentina Lo Sardo, Adam J Engler

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Conductive Microfibers Improve Stem Cell-Derived Cardiac Spheroid Maturation.Journal of biomedical materials research. Part A · 2025
    Article
  5. Review
  6. Review
  7. TheNon-coding RNA · 2023
    Article
  8. Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jaimie M MaynerChien-Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
Evan M MasutaniChien-Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
Elena DemeesterDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093.
Aditya KumarChien-Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
Gail MacapugayDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705.
Pranjali BeriChien-Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.
Valentina Lo SardoDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705.ORCID 0000-0003-0573-9878
Adam J EnglerChien-Lay Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0003-1642-5380
University of California San Diego · USUniversity of Wisconsin–Madison · US

Funding

Training Program in Basic Clinical GeneticsT32GM008666 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMILTON, BRUCE A · 1998 to 2021
$8.6M
Integrative Bioengineering of Heart, Vessels, and BloodT32HL105373 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, INTAGLIETTA, MARCOS · 2010 to 2019
$3.6M
Mechanogenetics: An Integrated Approach to Aging in Muscle DysfunctionR01AG045428 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ENGLER, ADAM J · 2013 to 2022
$3.4M
Illumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600k
NHLBI NIH HHS T32 HL105373NIA NIH HHS R01 AG045428NIGMS NIH HHS T32 GM008666NIH HHS S10 OD026929
6 · The paper itself

Abstract

9p21.3 locus polymorphisms have the strongest correlation with coronary artery disease, but as a noncoding locus, disease connection is enigmatic. The lncRNA

Indexed as

Coronary Artery DiseaseRNA, Long NoncodingCell PlasticityCell ProliferationCells, CulturedHumansMuscle, Smooth, VascularMyocytes, Smooth MusclePhenotypeRNA, Long NoncodingadhesioncontractilitylncRNAshear stresssorting

Identifiers

PMID37276403
PMCPMC10268236
OpenAlexW4379467440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.