Evidence map›Paper›PMID 37276086›Full record

ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2024

Reports of self-compassion and affect regulation in psilocybin-assisted therapy for alcohol use disorder: An interpretive phenomenological analysis.

Gabrielle Agin-Liebes, Elizabeth M Nielson, Michael Zingman, Katherine Kim, Alexandra Haas, Lindsey T Owens, Ursula Rogers, Michael Bogenschutz

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07737990 (Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07737990 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression

TypeinterventionalSponsorJoshua RosenblatRan2026 to 2030Enrolled65ConditionsTreatment-resistant Depression (TRD)ArmsGroup integration therapy
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gabrielle Agin-LiebesDepartment of Psychiatry, University of California, San Francisco.ORCID 0000-0002-9754-229X
Elizabeth M NielsonFluence.
Michael ZingmanNew York University Langone Center for Psychedelic Medicine, Department of Psychiatry, New York University Grossman School of Medicine.
Katherine KimNew York University Langone Center for Psychedelic Medicine, Department of Psychiatry, New York University Grossman School of Medicine.
Alexandra HaasDepartment of Psychiatry, University of California, San Francisco.
Lindsey T OwensNew York University Langone Center for Psychedelic Medicine, Department of Psychiatry, New York University Grossman School of Medicine.ORCID 0000-0001-7955-5209
Ursula RogersNew York University Langone Center for Psychedelic Medicine, Department of Psychiatry, New York University Grossman School of Medicine.
Michael BogenschutzNew York University Langone Center for Psychedelic Medicine, Department of Psychiatry, New York University Grossman School of Medicine.
New York University · USUniversity of California, San Francisco · US

Funding

BEHAVIORAL SCI TRAINING IN DRUG ABUSE RESEARCHT32DA007233 · NIDA · PUBLIC HEALTH SOLUTIONS · PI GOLDSAMT, LLOYD A · 1985 to 2023
$20.2M
Substance Use Disorders Treatment/Services Research Training ProgramT32DA007250 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Derek D Satre, Janice Y Tsoh · 1991 to 2026
$7.4M
NIDA NIH HHS T32 DA007233NIDA NIH HHS T32 DA007250NIH HHS
6 · The paper itself

Abstract

objectiveThe primary aim of this qualitative study was to delineate psychological mechanisms of change in the first randomized controlled trial of psilocybin-assisted psychotherapy to treat alcohol use disorder (AUD). Theories regarding psychological processes involved in psychedelic therapy remain underdeveloped.

methodParticipants (N = 13) mostly identified as non-Hispanic and White, with approximately equal proportions of cisgender men and women. Participants engaged in semistructured interviews about their subjective experiences in the study. Questions probed the nature of participants' drinking before and after the study as well as coping patterns in response to strong emotions, stress, and cravings for alcohol. Verbatim transcripts were coded using Dedoose software, and content was analyzed with interpretive phenomenological analysis.

resultsParticipants reported that the psilocybin treatment helped them process emotions related to painful past events and helped promote states of self-compassion, self-awareness, and feelings of interconnectedness. The acute states during the psilocybin sessions were described as laying the foundation for developing more self-compassionate regulation of negative affect. Participants also described newfound feelings of belonging and an improved quality of relationships following the treatment.

conclusionOur results support the assertion that psilocybin increases the malleability of self-related processing, and diminishes shame-based and self-critical thought patterns while improving affect regulation and reducing alcohol cravings. These findings suggest that psychosocial treatments that integrate self-compassion training with psychedelic therapy may serve as a useful tool for enhancing psychological outcomes in the treatment of AUD. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Indexed as

AlcoholismHallucinogensEmotionsFemaleHumansMalePsilocybinQualitative ResearchRandomized Controlled Trials as TopicSelf-CompassionHallucinogensPsilocybin

Identifiers

PMID37276086
PMCPMC10696130
OpenAlexW4379383539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.