Evidence map›Paper›PMID 37276013›Full record

ReviewInteractive journal of medical research2023

Heart Rate Variability and Pregnancy Complications: Systematic Review.

Zahra Sharifi-Heris, Amir M Rahmani, Anna Axelin, Mahkameh Rasouli, Miriam Bender

Abstract readReview
In one paragraph

Review in Interactive journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zahra Sharifi-Heris *University of California Irvine, Irvine, CA, United States.ORCID https://orcid.org/0000-0002-5526-1844
Amir M Rahmani *University of California Irvine, Irvine, CA, United States.ORCID https://orcid.org/0000-0003-0725-1155
Anna Axelin *University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0003-2743-3589
Mahkameh Rasouli *University of California Irvine, Irvine, CA, United States.ORCID https://orcid.org/0000-0002-7092-5880
Miriam Bender *University of California Irvine, Irvine, CA, United States.ORCID https://orcid.org/0000-0003-2457-1652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe autonomic nervous system (ANS) is known as a critical regulatory system for pregnancy-induced adaptations. If it fails to function, life-threatening pregnancy complications could occur. Hence, understanding and monitoring the underlying mechanism of action for these complications are necessary.

objectiveWe aimed to systematically review the literature concerned with the associations between heart rate variability (HRV), as an ANS biomarker, and pregnancy complications.

methodsWe performed a comprehensive search in the PubMed, Medline Completion, CINAHL Completion, Web of Science Core Collection Classic, Cochrane Library, and SCOPUS databases in February 2022 with no time span limitation. We included studies concerned with the association between any pregnancy complications and HRV, with or without a control group. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline was used for the review of the studies, and Covidence software was used for the study selection process. For data synthesis, we used the guideline by Popay et al.

resultsFinally, 12 studies with 6656 participants were included. Despite the methodological divergency that hindered a comprehensive comparison, our findings suggest that ANS is linked with some common pregnancy complications including fetal growth. However, existing studies do not support an association between ANS and gestational diabetes mellitus. Studies that linked pulmonary and central nervous system disorders with ANS function did not provide enough evidence to draw conclusions.

conclusionsThis review highlights the importance of understanding and monitoring the underlying mechanism of ANS in pregnancy-induced adaptations and the need for further research with robust methodology in this area.

Indexed as

autonomic nervous systemfetal growthglobal developmental delayheart rate variabilityhypertensionhypertensive disordermaternalpregnancypregnancy complication

Identifiers

PMID37276013
PMCPMC10280337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.