Evidence map›Paper›PMID 37275869›Full record

ArticleFrontiers in immunology2023

Effects of multiple pro-inflammatory stimuli

Julia Heiter, Matthew W Kemp, Owen B Spiller, Dominique Singer, John P Newnham, Suhas G Kallapur, Alan H Jobe, Boris W Kramer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 6 countries.

Julia HeiterDivision of Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands.
Matthew W KempDepartment of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Owen B SpillerDivision of Infection and Immunity, University Hospital of Wales, Cardiff, United Kingdom.
Dominique SingerDivision of Neonatology and Pediatric Critical Care Medicine, University Medical Center Eppendorf, Hamburg, Germany.
John P NewnhamUniversity of Western Australia, King Edward's Memorial Hospital, Crawley, WA, Australia.
Suhas G KallapurDivision of Neonatology and Developmental Biology at University of California, Los Angeles (UCLA) Health, Mattel Children's Hospital, Los Angeles, CA, United States.
Alan H JobeUniversity of Cincinnati, Cincinnati Children's Hospital, Cincinnati, OH, United States.
Boris W KramerDivision of Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Netherlands.
The University of Western Australia · AUUniversität Hamburg · DECincinnati Children's Hospital Medical Center · USNational University of Singapore · SGUniversity Hospital of Wales · GBUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chorioamnionitis is common in preterm birth and associated with a higher risk of intestinal inflammation and necrotizing enterocolitis. The intestinal inflammation influences the enteric nervous system development. We hypothesized that inflammation and innervation in the fetal ileum may be modified by chorioamnionitis induced by repeated challenge with lipopolysaccharide and/or preexisting Materials and methods: Time mated ovine fetuses were exposed by intraamniotic injections to chronic Results: Lipopolysaccharide exposure increased CD3 and myeloperoxidase-positive cells (p < 0.05). Repetitive exposure to lipopolysaccharide or combined Discussion: After exposure to chorioamnionitis induced by

Indexed as

ChorioamnionitisPremature BirthAnimalsFemaleFetusHumansInfantInfant, NewbornInflammationLipopolysaccharidesPregnancySheepSheep, DomesticLipopolysaccharideschorioamnionitisenteric nervous systemintestinal inflammationnecrotizing enterocolitispreterm fetal ileum

Identifiers

PMID37275869
PMCPMC10235639
OpenAlexW4377139088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.