Evidence map›Paper›PMID 37275861›Full record

ReviewFrontiers in immunology2023

Therapeutic strategies to enhance immune response induced by multiple myeloma cells.

Zhaoyun Liu, Chun Yang, Xiaohan Liu, Xintong Xu, Xianghong Zhao, Rong Fu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhaoyun LiuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Chun YangDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Xiaohan LiuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Xintong XuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Xianghong ZhaoDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Rong FuDepartment of Hematology, Tianjin Medical University General Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM)as a haematological malignancy is still incurable. In addition to the presence of somatic genetic mutations in myeloma patients, the presence of immunosuppressive microenvironment greatly affects the outcome of treatment. Although the discovery of immunotherapy makes it possible to break the risk of high toxicity and side effects of traditional chemotherapeutic drugs, there are still obstacles of ineffective treatment or disease recurrence. In this review, we discuss therapeutic strategies to further enhance the specific anti-tumor immune response by activating the immunogenicity of MM cells themselves. New ideas for future myeloma therapeutic approaches are provided.

Indexed as

Hematologic NeoplasmsMultiple MyelomaHumansImmunityImmunotherapyNeoplasm Recurrence, LocalTumor Microenvironmentimmunogenic cell deathimmunotherapymultiple myelomaneoantigenvaccine

Identifiers

PMID37275861
PMCPMC10232766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.