Evidence map›Paper›PMID 37275850›Full record

ArticleFrontiers in immunology2023

The chromatin reader protein ING5 is required for normal hematopoietic cell numbers in the fetal liver.

Sophia Y Y Mah, Hannah K Vanyai, Yuqing Yang, Anne K Voss, Tim Thomas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sophia Y Y MahEpigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Hannah K VanyaiEpigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Yuqing YangEpigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Anne K VossEpigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Tim ThomasEpigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
University of Melbourne · AUWalter and Eliza Hall Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ING5 is a component of KAT6A and KAT7 histone lysine acetylation protein complexes. ING5 contains a PHD domain that binds to histone H3 lysine 4 when it is trimethylated, and so functions as a 'reader' and adaptor protein. KAT6A and KAT7 function are critical for normal hematopoiesis. To examine the function of ING5 in hematopoiesis, we generated a null allele of

Indexed as

Hematopoietic Stem Cell TransplantationTranscription FactorsTumor Suppressor ProteinsAnimalsCell CountChromatinLiverLysineMiceChromatinLysineTranscription FactorsTumor Suppressor ProteinschromatinfetalhematopoiesisING5KAT6AKAT7

Identifiers

PMID37275850
PMCPMC10232820
OpenAlexW4377107907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.