Evidence map›Paper›PMID 37275673›Full record

ArticleHealth science reports2023

Alterations in lipid and hormonal titers in patients with acne and their relationship with severity: A case-control study.

Ghada Farouk Mohammed, Mohammed Saleh Al-Dhubaibi, Saleh Salem Bahaj, Ahmed Ibrahim AbdElneam

Abstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Alterations in the lipid profile in acne vulgaris patients: A meta-analysis.The Journal of international medical research · 2026
    Pooled it
  2. Article
  3. Review
  4. Acne vulgaris: a warning sign for diagnosing metabolic syndrome.Archives of dermatological research · 2024
    Article
  5. The role of hsa-miR-193a-5p as an important factor for control of inositol in alopecia areata.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  6. Article
  7. C-reactive protein as a novel biomarker for vitamin D deficiency in alopecia areata.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  8. MiR-200c-3p as a novel genetic marker and therapeutic tool for alopecia areata.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ghada Farouk MohammedDepartment of Dermatology, Venereology, and Sexology, Faculty of Medicine Suez Canal University Ismailia Egypt.ORCID 0000-0003-3074-1347
Mohammed Saleh Al-DhubaibiDepartment of Dermatology, Department of Medicine, College of Medicine Shaqra University Dawadmi Saudi Arabia.ORCID 0000-0002-6418-6647
Saleh Salem BahajDepartment of Microbiology and Immunology, Faculty of Medicine and Health Sciences Sana'a University Sana'a Yemen.ORCID 0000-0001-6582-907X
Ahmed Ibrahim AbdElneamDepartment of Clinical Biochemistry Shaqra University Dawadmi Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Acne is a frequently diagnosed skin condition that causes pilosebaceous apparatus clogs and/or inflammatory responses in the majority of teenagers. It is a multifactorial disease that can develop due to various factors. We aimed to evaluate lipid profiles and hormonal levels in patients with acne and correlate them to acne severity. We also aim to explore the alteration of lipid profiles and hormonal levels and their effect on the occurrence of acne. Methods: A case-control study was performed on 100 individuals with acne vulgaris and 100 healthy controls. The biochemical analysis included; lipid profiles such as triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), and hormonal levels such as estradiol (E), total testosterone (TT), and free testosterone (FT) were measured for both patients and controls. Results: Comparison between patients with acne and controls disclosed that; TC, TG, LDL-C, and HDL-C levels were significantly higher in patients, especially when compared to controls ( Conclusion: These altered lipid profiles and androgen levels should be considered in the pathophysiology of acne and taken into consideration when treating patients with acne.

Indexed as

acnecase‐control studyhormonal levelslipid profiles

Identifiers

PMID37275673
PMCPMC10234112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.