Evidence map›Paper›PMID 37275555›Full record

ArticleNeurobiology of sleep and circadian rhythms2023

Extracting continuous sleep depth from EEG data without machine learning.

Claus Metzner, Achim Schilling, Maximilian Traxdorf, Holger Schulze, Konstantin Tziridis, Patrick Krauss

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of sleep and circadian rhythms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Claus MetznerNeuroscience Lab, Experimental Otolaryngology, University Hospital, Erlangen, Germany.
Achim SchillingNeuroscience Lab, Experimental Otolaryngology, University Hospital, Erlangen, Germany.
Maximilian TraxdorfDepartment of Otorhinolaryngology, Head and Neck Surgery, Paracelsus Medical University, Nürnberg, Germany.
Holger SchulzeNeuroscience Lab, Experimental Otolaryngology, University Hospital, Erlangen, Germany.
Konstantin TziridisNeuroscience Lab, Experimental Otolaryngology, University Hospital, Erlangen, Germany.
Patrick KraussNeuroscience Lab, Experimental Otolaryngology, University Hospital, Erlangen, Germany.
Universitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEParacelsus Medizinische Privatuniversität · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human sleep-cycle has been divided into discrete sleep stages that can be recognized in electroencephalographic (EEG) and other bio-signals by trained specialists or machine learning systems. It is however unclear whether these human-defined stages can be re-discovered with unsupervised methods of data analysis, using only a minimal amount of generic pre-processing. Based on EEG data, recorded overnight from sleeping human subjects, we investigate the degree of clustering of the sleep stages using the General Discrimination Value as a quantitative measure of class separability. Virtually no clustering is found in the raw data, even after transforming the EEG signals of each 30-s epoch from the time domain into the more informative frequency domain. However, a Principal Component Analysis (PCA) of these epoch-wise frequency spectra reveals that the sleep stages separate significantly better in the low-dimensional sub-space of certain PCA components. In particular the component

Identifiers

PMID37275555
PMCPMC10238579
OpenAlexW4377090889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.