Evidence map›Paper›PMID 37275535›Full record

ArticleMarine life science & technology2023

Isolation and characterization of three pairs of verrucosidin epimers from the marine sediment-derived fungus

Yan-He Li, Attila Mándi, Hong-Lei Li, Xiao-Ming Li, Xin Li, Ling-Hong Meng, Sui-Qun Yang, Xiao-Shan Shi, Tibor Kurtán, Bin-Gui Wang

Abstract read
In one paragraph

Article in Marine life science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan-He LiCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Attila MándiDepartment of Organic Chemistry, University of Debrecen, Egyetem Tér 1, Debrecen, 4032 Hungary.
Hong-Lei LiCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Xiao-Ming LiCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Xin LiCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Ling-Hong MengCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Sui-Qun YangCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Xiao-Shan ShiCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.
Tibor KurtánDepartment of Organic Chemistry, University of Debrecen, Egyetem Tér 1, Debrecen, 4032 Hungary.
Bin-Gui WangCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology at the Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Verrucosidins, a methylated α-pyrone class of polyketides rarely reported upon, have been implicated in one or more neurological diseases. Despite the significance of verrucosidins as neurotoxins, the absolute configurations of most of the derivatives have not been accurately characterized yet. In this study, three pairs of C-9 epimeric verrucosidin derivatives, including the known compounds penicyrones A and B ( Supplementary Information: The online version contains supplementary material available at 10.1007/s42995-023-00173-2.

Indexed as

Antimicrobial activityMarine-derived fungusMosher’s methodPenicillium cyclopiumTDDFT-ECD calculationsVerrucosidin derivatives

Identifiers

PMID37275535
PMCPMC10232390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.