Evidence map›Paper›PMID 37275512›Full record

ArticleDrug target insights

Network analysis for identifying potential anti-virulence targets from whole transcriptome of

Feny J Ruparel, Siddhi K Shah, Jhanvi H Patel, Nidhi R Thakkar, Gemini N Gajera, Vijay O Kothari

Open access · goldAbstract read
In one paragraph

Article in Drug target insights. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Anti-QS Strategies AgainstMicroorganisms · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Feny J RuparelInstitute of Science, Nirma University, Ahmedabad - India.
Siddhi K ShahInstitute of Science, Nirma University, Ahmedabad - India.
Jhanvi H PatelInstitute of Science, Nirma University, Ahmedabad - India.
Nidhi R ThakkarInstitute of Science, Nirma University, Ahmedabad - India.
Gemini N GajeraInstitute of Science, Nirma University, Ahmedabad - India.
Vijay O KothariInstitute of Science, Nirma University, Ahmedabad - India.
Nirma University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Antimicrobial resistance (AMR) is a serious global threat. Identification of novel antibacterial targets is urgently warranted to help antimicrobial drug discovery programs. This study attempted identification of potential targets in two important pathogens Methods: Transcriptomes of Results: Genes associated with denitrification and sulfur metabolism emerged as the most important targets in Conclusion: Further validation of the potential targets identified in this study is warranted through appropriate

Indexed as

AMR (antimicrobial resistance)Anti-virulenceNetwork AnalysisNovel antibacterial targetsPolyherbalProtein-Protein Interaction (PPI)

Identifiers

PMID37275512
PMCPMC10238913
OpenAlexW4376137765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.