ArticleWorld journal of radiology2023
Chronic thromboembolic pulmonary hypertension is associated with a loss of total lung volume on computed tomography.
Article in World journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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10 authors at 1 institution in 1 country.
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Abstract
backgroundAlthough lung volumes are usually normal in individuals with chronic thromboembolic pulmonary hypertension (CTEPH), approximately 20%-29% of patients exhibit a restrictive pattern on pulmonary function testing.
aimTo quantify longitudinal changes in lung volume and cardiac cross-sectional area (CSA) in patients with CTEPH.
methodsIn a retrospective cohort study of patients seen in our hospital between January 2012 and December 2019, we evaluated 15 patients with CTEPH who had chest computed tomography (CT) performed at baseline and after at least 6 mo of therapy. We matched the CTEPH cohort with 45 control patients by age, sex, and observation period. CT-based lung volumes and maximum cardiac CSAs were measured and compared using the Wilcoxon signed-rank test and the Mann-Whitney
resultsTotal, right lung, and right lower lobe volumes were significantly reduced in the CTEPH cohort at follow-up
conclusionAfter at least 6 mo of treatment, CT showed an unexpected loss of total lung volume in patients with CTEPH that may reflect continued parenchymal remodeling.
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