ArticleArchives of Razi Institute2022
The Protective Effect of Turmeric against Carbimazole Induced Toxicity in Male Rats.
Article in Archives of Razi Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- Hesperidin alleviates hypothyroidism-related cardiac dysfunction by targeting cardiac miRNAs, Nrf2/NF-κB signaling, oxidative stress and inflammation.Frontiers in pharmacology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbimazole is a widespread drug utilized for treating hyperthyroidism. However, carbimazole usage could be associated with adverse effects such as liver damage and nephritis in rats. At the same time, turmeric, as a medical plant, has many antioxidant effects against liver and kidney toxicity. This study aimed to explore the protective effect of turmeric against carbimazole-induced toxicity in rats. The experiment was carried out on 24 male Wistar rats. They were separated into four groups, each with six animals, as follows: 1. Control group: represents a healthy animal, and each rat is only given standard food and distilled water for 30 days. 2. Carbimazole group: drenched orally 0.5 mg carbimazole daily for 30 days. 3. Turmeric group: drenched orally 100 mg turmeric powder daily for 30 days. 4. Carbimazole and turmeric group: drenched orally carbimazole 0.5 mg and turmeric 100 mg daily for 30 days. The study demonstrated a significant effect of turmeric powder in reducing the toxicity of carbimazole in both the kidney and liver biochemical parameters, in addition to the evidence of histological sections. Turmeric powder has the ability to reduce and prevent renal and hepatic toxicity induced by carbimazole overdose, which gives turmeric medical value.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.