Evidence map›Paper›PMID 37274530›Full record

ArticleOpen forum infectious diseases2023

Seroepidemiology for Enteric Fever: Emerging Approaches and Opportunities.

Kristen Aiemjoy, Jessica C Seidman, Richelle C Charles, Jason R Andrews

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristen AiemjoyDivision of Epidemiology, Department of Public Health Sciences, University of California, Davis School of Medicine, Davis, California, USA.ORCID https://orcid.org/0000-0003-1886-2699
Jessica C SeidmanSabin Vaccine Institute, Washington, District of Columbia, USA.
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.
Jason R AndrewsDivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID https://orcid.org/0000-0002-5967-251X

Funding

Estimating the Seroincidence of Melioidosis, Typhoid Fever and Scrub Typhus from Cross-sectional SerosurveysK01TW012177 · FIC · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Kristen Aiemjoy · 2022 to 2026
$901k
FIC NIH HHS K01 TW012177NIAID NIH HHS L30 AI147158
6 · The paper itself

Abstract

Safe and effective typhoid conjugate vaccines (TCVs) are available, but many countries lack the high-resolution data needed to prioritize TCV introduction to the highest-risk communities. Here we discuss seroepidemiology-an approach using antibody response data to characterize infection burden-as a potential tool to fill this data gap. Serologic tests for typhoid have existed for over a hundred years, but only recently were antigens identified that were sensitive and specific enough to use as epidemiologic markers. These antigens, coupled with new methodological developments, permit estimating seroincidence-the rate at which new infections occur in a population-from cross-sectional serosurveys. These new tools open up many possible applications for enteric fever seroepidemiology, including generating high-resolution surveillance data, monitoring vaccine impact, and integrating with other serosurveillance initiatives. Challenges remain, including distinguishing

Indexed as

disease burdenenteric feverseroepidemiologyserosurveillancetyphoid

Identifiers

PMID37274530
PMCPMC10236506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.