Evidence map›Paper›PMID 37274364›Full record

ArticleInfection and drug resistance2023

Clinical Characteristics and Outcomes of Vaccinated VS Non-Vaccinated Critically Ill COVID-19 Patients: Retrospective Observation Study.

Shaya Yaanallah AlQahtani, Ahmed Anwer Alabdulqader, Waleed Abdulrahman Al Mashhour, Zahra Mohammed Aldawood, Osama Ali Al Masari, Thabit Alotaibi, Zeead M AlGhamdi, Ibrahim M Alzahrani, Noor Nabil Albaloushi

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Shaya Yaanallah AlQahtaniDepartment of Internal Medicine and Critical Care Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-8038-9700
Ahmed Anwer AlabdulqaderKing Fahad Hospital Hofuf, Hofuf, Saudi Arabia.
Waleed Abdulrahman Al MashhourDammam Medical Complex, Dammam, Saudi Arabia.
Zahra Mohammed AldawoodKing Khalid Hospital- AlKharaj, Alkharaj, Saudi Arabia.
Osama Ali Al MasariDepartment of Internal Medicine and Critical Care Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-7382-5682
Thabit AlotaibiDepartment of Internal Medicine and Critical Care Medicine, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Zeead M AlGhamdiThoracic Surgery Division, Department of Surgery, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0002-0096-4921
Ibrahim M AlzahraniDepartment of Internal medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.ORCID 0000-0003-4159-7061
Noor Nabil AlbaloushiMinistry of Health, Dammam, Saudi Arabia.
Imam Abdulrahman Bin Faisal University · SADammam Central Hospital · SAKing Fahad Hospital Hufūf · SAKing Khaled Hospital · SAMinistry of Health · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aim to identify the clinical characteristics and outcome of vaccine breakthrough infection in critically ill COVID-19 patients and to compare the clinical course of disease between vaccinated and non-vaccinated patients. Methods: A retrospective review of all adult patients aged ≥18 years admitted to the ICU in King Fahd Hospital of the University in Saudi Arabia with positive COVID-19 RT-PCR test between the period of January 1st to August 31st, 2021, were included. The recruited patients were grouped in to "vaccinated and non-vaccinated group" based on their immunization status. The demographic data, co-morbidities, modality of oxygen support, ICU length of stay (ICU LOS) and mortality were collected and analyzed. Results: A total of 167 patients were included. Seventy-two patients (43%) were vaccinated. Cardiovascular diseases were higher among the vaccinated group (33.3% vs 12.6%, Conclusion: In critically ill COVID-19 patients, the vaccinated group has significantly less need for Non-invasive ventilation, fewer intubation days and less hypoxia compared to non-vaccinated patients. We recommend more policies and public education nationwide and worldwide to encourage vaccination and raise awareness of the general population.

Indexed as

breakthrough infectionCOVID-19 vaccineinflammatory markersintensive care unitvaccine effectiveness

Identifiers

PMID37274364
PMCPMC10237627
OpenAlexW4378627724

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.