Evidence map›Paper›PMID 37274357›Full record

ArticleInfection and drug resistance2023

Tuberculosis Treatment Outcome and Associated Factors Among Tuberculosis Patients Linked to Tuberculosis Treatment Clinics in Ethiopia, 2023: A Multi-Center Retrospective Study.

Ayenew Berhan, Andargachew Almaw, Yenealem Solomon, Biruk Legese, Shewaneh Damtie, Mulat Erkihun, Zewuditu Alebachew, Tahir Eyayu, Getu Abeje, Birhanu Getie

Abstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ayenew BerhanMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-2244-4476
Andargachew AlmawMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-4895-3017
Yenealem SolomonMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-2033-5663
Biruk LegeseMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-1315-7192
Shewaneh DamtieMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-2156-2438
Mulat ErkihunMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Zewuditu AlebachewMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Tahir EyayuMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0002-2041-7183
Getu AbejeBiomedical Sciences, College of Health Sciences, Samara University, Samara, Ethiopia.ORCID 0000-0003-1624-3464
Birhanu GetieMedical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tuberculosis is a communicable disease, mainly caused by the bacillus Mycobacterium tuberculosis. Globally, TB is the ninth leading cause of death, with developing countries bearing most of the burden. The discovery of chemotherapy lead to significant improvements in patient survival. Therefore, this study aimed to assess Tuberculosis treatment outcomes and associated factors in South Gondar Administrative Zone Governmental Hospitals, Northwest Ethiopia, 2023. Method and Materials: A hospital-based retrospective study was conducted from July 1 to August 30, 2022, at South Gondar zone public hospitals. The data was entered into Epi-data version 4 and exported to STATA version 14. A binary and multivariable logistic regression was computed at a 95% confidence interval. Variables with a p-value less than 0.25 in the bivariable analysis were chosen for multivariable logistic regression analysis, and variables having a p-value of less than 0.05 in the multivariable analysis, were considered to have significant associations with the dependent variable. Results: The study included 400 tuberculosis patients, and the overall successful treatment outcome was 89.0% (95% Confidence Interval: 85.5-91.7). In this study, study participants who tested positive for HIV were approximately three times more likely to have unsuccessful treatment outcomes (Adjusted odds ratio = 3.07; 95% Confidence Interval = 1.49-6.16.5; P = 0.002) relative to HIV-negative patients. On the other hand, patients with sputum-positive were more likely to have a successful treatment rate (Adjusted odds ratio = 0.08; 95% Confidence Interval = 0.011-0.638, P = 0.002) relative to sputum-negative TB patients. Conclusion: The overall treatment success rate was 89.0%, which was lower than the global milestone target of > 90% set for 2025, and the prevalence of TB-HIV coinfection was 16.5%. In this study, HIV-positive was negatively associated with successful treatment outcomes, and sputum positive was independently associated with successful tuberculosis treatment outcomes.

Indexed as

Ethiopiapatienttreatment outcometuberculosis

Identifiers

PMID37274357
PMCPMC10239251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.