Evidence map›Paper›PMID 37274220›Full record

ArticleFrontiers in neuroscience2023

Sleep deprivation, sleep fragmentation, and social jet lag increase temperature preference in

S Tanner Roach, Melanie C Ford, Vikram Simhambhatla, Vasilios Loutrianakis, Hamza Farah, Zhaoyi Li, Erica M Periandri, Dina Abdalla, Irene Huang, Arjan Kalra and 1 more

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S Tanner RoachDepartment of Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, United States.
Melanie C FordDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Vikram SimhambhatlaDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Vasilios LoutrianakisDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Hamza FarahDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Zhaoyi LiDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Erica M PeriandriDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Dina AbdallaDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Irene HuangDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Arjan KalraDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.
Paul J ShawDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the fact that sleep deprivation substantially affects the way animals regulate their body temperature, the specific mechanisms behind this phenomenon are not well understood. In both mammals and flies, neural circuits regulating sleep and thermoregulation overlap, suggesting an interdependence that may be relevant for sleep function. To investigate this relationship further, we exposed flies to 12 h of sleep deprivation, or 48 h of sleep fragmentation and evaluated temperature preference in a thermal gradient. Flies exposed to 12 h of sleep deprivation chose warmer temperatures after sleep deprivation. Importantly, sleep fragmentation, which prevents flies from entering deeper stages of sleep, but does not activate sleep homeostatic mechanisms nor induce impairments in short-term memory also resulted in flies choosing warmer temperatures. To identify the underlying neuronal circuits, we used RNAi to knock down the receptor for

Indexed as

Drosophilasleepsleep deprivationsleep fragmentationtemperature preference behavior

Identifiers

PMID37274220
PMCPMC10237294

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.