Evidence map›Paper›PMID 37274111›Full record

ReviewFrontiers in pharmacology2023

A review of nanomaterials from synthetic and natural molecules for prospective breast cancer nanotherapy.

Pankaj Kumar, Bharti Mangla, Shamama Javed, Waquar Ahsan, Pankaj Musyuni, Durgaramani Sivadasan, Saad S Alqahtani, Geeta Aggarwal

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Selenium-Containing Compounds in Breast Cancer Therapy.Biological trace element research · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Development andNanomedicine (London, England) · 2025
    Article
  7. Review
  8. Review
  9. Nanoparticle-Mediated Immunotherapy in Triple-Negative Breast Cancer.ACS biomaterials science & engineering · 2024
    Review
  10. A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Pankaj KumarCentre For Advanced Formulation and Technology, Delhi Pharmaceutical Sciences and Research University, New Delhi, India.
Bharti ManglaCentre For Advanced Formulation and Technology, Delhi Pharmaceutical Sciences and Research University, New Delhi, India.
Shamama JavedDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Waquar AhsanDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Pankaj MusyuniCentre For Advanced Formulation and Technology, Delhi Pharmaceutical Sciences and Research University, New Delhi, India.
Durgaramani SivadasanDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Saad S AlqahtaniDepartment of Clinical Pharmacy, College of Pharmacy, Jazan University, Jazan, Saudi Arabia.
Geeta AggarwalCentre For Advanced Formulation and Technology, Delhi Pharmaceutical Sciences and Research University, New Delhi, India.
Delhi Pharmaceutical Science and Research University · INJazan University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer being one of the most frequent cancers in women accounts for almost a quarter of all cancer cases. Early and late-stage breast cancer outcomes have improved dramatically, with considerable gains in overall survival rate and disease-free state. However, the current therapy of breast cancer suffers from drug resistance leading to relapse and recurrence of the disease. Also, the currently used synthetic and natural agents have bioavailability issues which limit their use. Recently, nanocarriers-assisted delivery of synthetic and natural anticancer drugs has been introduced to the breast cancer therapy which alienates the limitations associated with the current therapy to a great extent. Significant progress has lately been made in the realm of nanotechnology, which proved to be vital in the fight against drug resistance. Nanotechnology has been successfully applied in the effective and improved therapy of different forms of breast cancer including invasive, non-invasive as well as triple negative breast cancer (TNBC), etc. This review presents a comprehensive overview of various nanoformulations prepared for the improved delivery of synthetic and natural anticancer drugs alone or in combination showing better efficacy and pharmacokinetics. In addition to this, various ongoing and completed clinical studies and patents granted on nanotechnology-based breast cancer drug delivery are also reviewed.

Indexed as

anticancer drugsbreast cancerdrug deliverynanocarriersphytochemicalssynthetic

Identifiers

PMID37274111
PMCPMC10237355
OpenAlexW4377097543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.