ReviewWorld journal of gastroenterology2023
Current trends in acute pancreatitis: Diagnostic and therapeutic challenges.
Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 2 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Inflammatory bowel disease increases the risk of pancreatitis: a two-sample bidirectional Mendelian randomization analysis.BMC gastroenterology · 2025Pooled it
- MiRNA-loaded MSC exosomes restore autophagy flux for acute pancreatitis therapy.Frontiers in immunology · 2025Pooled it
- Impact of early blood purification on serum inflammatory mediators and hemorheology in severe acute pancreatitis.Hereditas · 2025Trial
- Trial
- Application of psychological intervention in intensive care unit nursing for patients with severe acute pancreatitis.World journal of psychiatry · 2024Trial
- Sirtuin 2 Contributes to Pancreatic Injury and Inflammation by Modulating Immediate Early Response 3-Mediated Ferroptosis in Acute Pancreatitis.Cellular and molecular gastroenterology and hepatology · 2026Article
- The IL-33/ST2 Signaling Axis Alleviates Splenic Injury in Severe Acute Pancreatitis by Inhibiting T-Cell Ferroptosis.Pancreas · 2026Article
- Prognostic Value of Albumin-Bilirubin Score in Acute Pancreatitis: Insights From the MIMIC-IV Database.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Gut or Vein? Enteral Nutrition Versus Total Parenteral Nutrition in Acute Pancreatitis: A Systematic Review.Cureus · 2026Review
- Article
- The role and regulatory mechanism of USP25 in pancreatic microcirculatory disturbance in severe acute pancreatitis.Scientific reports · 2026Article
- Loss of daily phase relations identified by multiomic analyses in acute pancreatitis.Biochemistry and biophysics reports · 2026Article
- Article
- Dietary Cannabis Seed Supplementation Attenuates Inflammation and Pancreatic Injury in a Cerulein-Induced Acute Pancreatitis Mouse Model.Current issues in molecular biology · 2026Article
- Development of a hemodynamic scoring system for acute pancreatitis: an exploratory approach to optimizing fluid resuscitation.BMC gastroenterology · 2026Article
- Homoplantaginin protects pancreatic tissue in severe acute pancreatitis mice via inhibiting ferroptosis by modulating the circDNMT3B/miR-20b-5p/SLC7A11 axis.BMC gastroenterology · 2026Article
- MiR-324-5p mitigates experimental acute pancreatitis by suppressing Rock2 expression.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- The role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in predicting the severity of acute biliary pancreatitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Integrative multi-omics profiling reveals coordinated immunometabolic reprogramming and host-microbiome interactions in acute pancreatitis.Frontiers in immunology · 2026Article
- Clinical and Biochemical Characteristics of Traditional Chinese Medicine Syndromes in Acute Pancreatitis: A Two-Center Retrospective Study.International journal of general medicine · 2026Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute pancreatitis (AP) is an inflammatory disease of the pancreas, which can progress to severe AP, with a high risk of death. It is one of the most complicated and clinically challenging of all disorders affecting the abdomen. The main causes of AP are gallstone migration and alcohol abuse. Other causes are uncommon, controversial and insufficiently explained. The disease is primarily characterized by inappropriate activation of trypsinogen, infiltration of inflammatory cells, and destruction of secretory cells. According to the revised Atlanta classification, severity of the disease is categorized into three levels: Mild, moderately severe and severe, depending upon organ failure and local as well as systemic complications. Various methods have been used for predicting the severity of AP and its outcome, such as clinical evaluation, imaging evaluation and testing of various biochemical markers. However, AP is a very complex disease and despite the fact that there are of several clinical, biochemical and imaging criteria for assessment of severity of AP, it is not an easy task to predict its subsequent course. Therefore, there are existing controversies regarding diagnostic and therapeutic modalities, their effectiveness and complications in the treatment of AP. The main reason being the fact, that the pathophysiologic mechanisms of AP have not been fully elucidated and need to be studied further. In this editorial article, we discuss the efficacy of the existing diagnostic and therapeutic modalities, complications and treatment failure in the management of AP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.