Identification of Different Profiles of Illness Perception in COPD Patients: Results of Cluster Analysis.

Background: Chronic obstructive pulmonary disease (COPD) is a widespread, late-diagnosed, and difficult-to-treat disease that influences the quality of life. Despite the availability of a wide range of drugs for the treatment of COPD, none of them provides a complete cure, while the leading risk factors (primarily, smoking) persist. In this regard, illness perception and medical behavior play a key role. Methods: The study design was cross-sectional and included 143 stable outpatients (107 men, mean age 66 ± 7.5, FEV1 51.5 ± 16.5%) who attended the faculty therapy clinic of Sechenov University. The patients were examined pulmonologically and psychiatrically (Hamilton depression and anxiety rating scales). Illness perception was assessed by a brief version of the Illness perception questionnaire (brief IPQ). Results: There were no significant demographic differences and differences in the clinical severity of the disease between the selected groups. Patients in the distressed group had a longer duration of illness, a higher prevalence of anxiety and depression, and more severe dyspnea after a 6-minute walk test. In contrast, patients in the disregarding group had a significantly higher prevalence of smokers and a higher number of cigarettes smoked daily, and a lower prevalence of anxiety and depression. The harmonic had the most optimal profile with low severity of anxiety and depression, but with a healthier attitude to smoking. Conclusion: Perception of illness in COPD patients has a significant impact on medical behavior and levels of anxiety and depression. As such, the perception of illness deserves routine monitoring in clinical practice.