Evidence map›Paper›PMID 37273916›Full record

ArticleOpen medicine (Warsaw, Poland)2023

Vitamin D protects intestines from liver cirrhosis-induced inflammation and oxidative stress by inhibiting the TLR4/MyD88/NF-κB signaling pathway.

Mei Luo, Yuanhong Xu, Jike Li, Dongxia Luo, Li Zhu, Yanxi Wu, Xiaodong Liu, Pengfei Wu

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mei LuoInfectious Disease Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Yuanhong XuClinical Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Jike LiInfectious Disease Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Dongxia LuoInfectious Disease Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Li ZhuHepatology Clinic, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Yanxi WuInfectious Disease Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Xiaodong LiuClinical Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Pengfei WuInfectious Disease Laboratory, Chengdu Public Health Clinical Center, Chengdu, 610061, China.
Public Health Clinical Center of Chengdu · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis affects the structures and physiological functions of the intestine. Our previous study revealed that liver injury inhibited 25-hydroxylation of vitamin D (25(OH)-VD). The aim of this study was to investigate the roles and mechanisms of vitamin D in liver cirrhosis-induced intestinal injury. The rat liver cirrhosis model was established through the administration of carbon tetrachloride (CCl

Indexed as

intestinal injuryliver cirrhosisoxidative stressvitamin Dα-defensin 5

Identifiers

PMID37273916
PMCPMC10238812
OpenAlexW4378717005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.