Evidence map›Paper›PMID 37273829›Full record

ReviewFrontiers in surgery2023

The effect of the enhanced recovery after surgery program on radical cystectomy: a meta-analysis and systematic review.

Yongheng Zhou, Rongyang Li, Zhifeng Liu, Wenqiang Qi, Guangda Lv, Minglei Zhong, Xigao Liu, Meikai Zhu, Zhiwen Jiang, Shouzhen Chen and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yongheng ZhouDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Rongyang LiDepartment of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan, China.
Zhifeng LiuDepartment of Urology Surgery, Taian City Central Hospital, Taian, China.
Wenqiang QiDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Guangda LvDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Minglei ZhongDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Xigao LiuDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Meikai ZhuDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Zhiwen JiangDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Shouzhen ChenDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Benkang ShiDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Yaofeng ZhuDepartment of Urology, Qilu Hospital of Shandong University, Jinan, China.
Qilu Hospital of Shandong University · CNTaian City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bladder cancer is the ninth most common malignant tumor worldwide. As an effective evidence-based multidisciplinary protocol, the enhanced recovery after surgery (ERAS) program is practiced in many surgical disciplines. However, the function of ERAS after radical cystectomy remains controversial. This systematic review and meta-analysis aims to research the impact of ERAS on radical cystectomy. Methods: A systematic literature search on PubMed, EMBASE, SCOPUS, and the Cochrane Library databases was conducted in April 2022 to identify the studies that performed the ERAS program in radical cystectomy. Studies were selected, data extraction was performed independently by two reviewers, and quality was assessed using a random effects model to calculate the overall effect size. The odds ratio and standardized mean difference (SMD) with a 95% confidence interval (CI) served as the summary statistics for the meta-analysis. A sensitivity analysis was subsequently performed. Results: A total of 25 studies with 4,083 patients were enrolled. The meta-analysis showed that the complications (OR = 0.76; 95% CI: 0.63-0.90), transfusion rate (OR = 0.59; 95% CI: 0.39-0.90), readmission rate (OR = 0.79; 95% CI: 0.64-0.96), length of stay (SMD = -0.79; 95% CI: -1.41 to -0.17), and time to first flatus (SMD = -1.16; 95% CI: -1.58 to -0.74) were significantly reduced in the ERAS group. However, no significance was found in 90-day mortality and urine leakage. Conclusion: The ERAS program for radical cystectomy can effectively decrease the risk of overall complications, postoperative ileus, readmission rate, transfusion rate, length of stay, and time to first flatus in patients who underwent radical cystectomy with relative safety. Systematic Review Registration: https://inplasy.com/, identifier INPLASY202250075.

Indexed as

bladder cancerenhanced recovery after surgery (ERAS)meta-analysisradical cystectomysystematic review

Identifiers

PMID37273829
PMCPMC10235530
OpenAlexW4377138795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.