Evidence map›Paper›PMID 37273763›Full record

ArticleOpen access rheumatology : research and reviews2023

Expert Opinion Guidance on the Detection of Early Connective Tissue Diseases in Interstitial Lung Disease.

Rajaie Namas, Mohamed Elarabi, Fouad Fayad, Aqeel A Muhanna Ghanem, Adeeba Al-Herz, Waleed Hafiz, Abhay Joshi, Mira Merashli, Jad Okais, Imad Uthman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open access rheumatology : research and reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Rajaie NamasDepartment of Internal Medicine, Division of Rheumatology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-0353-895X
Mohamed ElarabiDepartment of Internal Medicine, Division of Rheumatology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Fouad FayadRheumatology Department, Hotel-Dieu de France Hospital, Lebanon and Saint Joseph University of Beirut-Beirut (Lebanon), Beirut, Lebanon.
Aqeel A Muhanna GhanemRheumatology Unit, Mubarak Al Kabeer Hospital, Jabriya, Kuwait.
Adeeba Al-HerzDepartment of Rheumatology, Amiri Hospital, Kuwait City, Kuwait.ORCID 0000-0001-7059-1385
Waleed HafizDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.ORCID 0000-0001-9608-6248
Abhay JoshiDepartment of Rheumatology, Burjeel Day Surgery, Abu Dhabi, United Arab Emirates.
Mira MerashliDivision of Rheumatology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
Jad OkaisRheumatology Department, Hotel-Dieu de France Hospital, Lebanon and Saint Joseph University of Beirut-Beirut (Lebanon), Beirut, Lebanon.
Imad UthmanDivision of Rheumatology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.ORCID 0000-0001-8285-6483
Khuloud Saleh EssaRheumatology Unit, Farwaniya Hospital, Kuwait City, Kuwait.
Mohammed A OmairDepartment of Medicine, King Saud University, Riyadh, Saudi.ORCID 0000-0002-9373-5473
American University of Beirut · LBSaint Joseph University · LBAmiri Hospital · KWEmirates Foundation · AEFarwaniya Hospital · KWKing Saud University · SAMubarak Al Kabeer Hospital · KWUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a significant variation in symptoms and clinical presentation of connective tissue disorders (CTD) associated with interstitial lung disease (ILD) (CTD-ILD). This presents difficulties in the diagnosis and treatment of CTD-ILD. Early detection and treatment of CTD-ILD using a multidisciplinary approach have been shown to enhance patient outcomes. This exercise aims to explore clinical components to develop a screening tool for pulmonologists for early detection of CTD in ILD and to provide a framework for a multidisciplinary approach in managing CTD-ILD. This in turn will lead to early treatment of CTD-ILD in collaboration with rheumatologists. A panel of 12 leading rheumatologists from the Middle East and North Africa (MENA) region met virtually to select the most relevant clinical findings to aid in identifying CTD-ILD. Twelve panellists opted to investigate seven of the most common inflammatory autoimmune disorders. The panel discussed how to improve the early detection of CTD-ILD. Clinical characteristics were categorized, and a nine-item questionnaire was created. A biphasic algorithm was developed to guide early referral to a rheumatologist based on the presence of one of nine clinical features of CTD (Phase 1) or the presence of CTD-specific antibodies (Phase 2). A brief questionnaire has been developed to serve as a simple and practical screening tool for CTD-ILD detection. Additional research is needed to validate and evaluate the tool in longitudinal cohorts.

Indexed as

connective tissue disease-associated interstitial lung diseaseCTD-ILDmultidisciplinary teampulmonologistsrheumatologistsscreening

Identifiers

PMID37273763
PMCPMC10237281
OpenAlexW4378627671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.