Evidence map›Paper›PMID 37273693›Full record

ArticleFrontiers in neurology2023

Stress hyperglycemia as a modifiable predictor of futile recanalization in patients undergoing mechanical thrombectomy for acute ischemic stroke.

Giovanni Merlino, Sara Pez, Roberto Sartor, Fedra Kuris, Yan Tereshko, Lorenzo Nesi, Simone Lorenzut, Francesco Janes, Massimo Sponza, Vladimir Gavrilovic and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Giovanni MerlinoStroke Unit, Department of Head-Neck and Neuroscience, Udine University Hospital, Udine, Italy.
Sara PezClinical Neurology, Udine University Hospital, Udine, Italy.
Roberto SartorClinical Neurology, Udine University Hospital, Udine, Italy.
Fedra KurisClinical Neurology, Udine University Hospital, Udine, Italy.
Yan TereshkoClinical Neurology, Udine University Hospital, Udine, Italy.
Lorenzo NesiClinical Neurology, Udine University Hospital, Udine, Italy.
Simone LorenzutStroke Unit, Department of Head-Neck and Neuroscience, Udine University Hospital, Udine, Italy.
Francesco JanesStroke Unit, Department of Head-Neck and Neuroscience, Udine University Hospital, Udine, Italy.
Massimo SponzaDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Vladimir GavrilovicDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Nicola MarottiDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Andrea PellegrinDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Annarita DapotoDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Alessandro VitDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Alessandro PauroDivision of Vascular and Interventional Radiology, Udine University Hospital, Udine, Italy.
Gian Luigi GigliDipartimento di Area Medica (DAME), University of Udine, Udine, Italy.
Mariarosaria ValenteClinical Neurology, Udine University Hospital, Udine, Italy.
University of Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Mechanical thrombectomy (MT) is the first line treatment in acute ischemic stroke (AIS) due to large vessel occlusion (LVO). Approximately half of patients treated with MT does not have a favorable outcome 3 months after stroke. The aim of this study was to identify predictors of futile recanalization (FR) in patients with LVO treated with MT. Methods: A retrospective analysis of consecutive patients with acute ischemic stroke due to anterior circulation LVO who underwent MT. Patients with a TICI score of 2b or 3 were included. We distinguished two groups, FR and meaningful recanalization (MR), according to patients' disability three months after stroke (FR: mRS score > 2; MR: mRS score < 2). Results: We enrolled 238 patients (FR, Discussion: FR is common after MT. We recognized older age, female sex and baseline NIHSS as non-modifiable predictors of FR. On the other hand, time from symptoms onset to MT and stress hyperglycemia were modifiable pre- and post-MT factors, respectively. Any effort should be encouraged to reduce the impact of these modifiable predictors.

Indexed as

acute ischemic strokefutile recanalizationlarge vessel occlusionmechanical thrombectomystress hyperglycemia

Identifiers

PMID37273693
PMCPMC10235599
OpenAlexW4377139919

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.